Hydrogen peroxide 35% solution
Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2.
Official documents, adverse reaction reporting, and safety monitoring
Report a side effect
Submit a Yellow Card report to the MHRA
Official medicine documents
Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
View Drug Analysis Profile
Suspected adverse reactions reported for Hydrogen peroxide
Browse all iDAP reports
Interactive Drug Analysis Profiles for all medicines
Report a side effect
Submit a Yellow Card report to the MHRA
Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.
View EudraVigilance report
Suspected adverse reactions reported for Hydrogen peroxide
About EudraVigilance
Learn about EU pharmacovigilance and safety monitoring
EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
1 branded products available
Therapeutically similar medicines
Similarity based on WHO Anatomical Therapeutic Chemical (ATC) classification and NHS BNF section grouping. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.
NHS prescribing volume and spending trends
Clinical guidelines and formulary information
British National Formulary
Hydrogen peroxide
Source: British National Formulary, NICE. Joint Formulary Committee. Contains public sector information licensed under the Open Government Licence v3.0.
NICE clinical guidance(6)
Impetigo: antimicrobial prescribing (NG153)
Collagen paste for closing an anal fistula (HTG512)
Leg ulcer infection: antimicrobial prescribing (NG152)
Permacol for treating anal fistulae (MIB105)
Oxyzyme and Iodozyme 2-layer hydrogel wound dressings with iodine for treating chronic wounds (MIB11)
RIDASCREEN tests for monitoring infliximab in inflammatory bowel disease (MIB109)
Source: National Institute for Health and Care Excellence (NICE). Contains public sector information licensed under the Open Government Licence v3.0.
Check stock at pharmacies and supply information
Pharmacy stock checkers
Search for this medicine at major UK pharmacy chains. These links open the retailer's own website — results depend on their current online catalogue.
Supply & product information
Official product databases and supply status monitoring
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. emc (electronic medicines compendium) is operated by Datapharm Ltd. Shortage information sourced from NHS Specialist Pharmacy Service (SPS), sps.nhs.uk.
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
Browse tools
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF codes from NHS Business Services Authority (NHSBSA). ATC codes from the WHO Collaborating Centre for Drug Statistics Methodology (whocc.no).
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
None known
Half-life
Not available
Mechanism
The production of free hydroxyl radicals in the Fenton reaction is thought to be…
Food interactions
None known
Human targets
1 target
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Absorption
Volume of distribution
[L2024]
Metabolism
Pharmacokinetic data: DrugBank · CC BY-NC 4.0
Due to its potent and broad-spectrum antimicrobial actions, hydrogen peroxide is used in both liquid and gas form for preservative, disinfection and sterilization applications as an oxidative biocide [A32369]. It is used in industrial and cosmetic applications as a bleaching agent. Hydrogen peroxide is also considered as a generally recognized as safe compound by the FDA [L2024]; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing agent in products containing dried eggs, dried egg whites, and dried egg yolks.
Known interactions with other medications. Always consult a healthcare professional.
Showing 50 of 58 interactions
Oral ingestion of high dose hydrogen peroxide may cause chest and stomach pain, loss of consciousness, motor disorders, microhemorrhages and moderate leucocytosis in humans. Inhalation of highly concentrated vapours causes extreme irritation of nose and throat .
[L2024]
Hydrogen peroxide has no known carcinogenic potential.
It was shown to be mutagenic to bacteria (Salmonella typhimurium) and the fungi, Neurospora crassa and Aspergillis chevallieri, and induced DNA damage in Escheria coli .
[L2024]
It also caused sister chromatid exchanges and chromosomal aberrations in mammalian cells in vitro .
[L2024]
How the body processes this drug — absorption, distribution, metabolism, and elimination
[L2024]
[L2024]
[L2024]
Proteins and enzymes this drug interacts with in the body
May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET
Enzymes involved in drug metabolism — important for understanding drug interactions
ATC D08AX01
ATC S02AA06
ATC D11AX25
ATC A01AB02
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Show
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Linked compound data from DrugBank Open Data (CC BY-NC 4.0)
Hydrogen peroxide
Additional database identifiers
Drugs Product Database (DPD)
7128
ChemSpider
763
PDB
PEO
HUGO Gene Nomenclature Committee (HGNC)
HGNC:9642
GenAtlas
PTPN1
GeneCards
PTPN1
GenBank Gene Database
M31724
GenBank Protein Database
190742
Guide to Pharmacology
2976
UniProt Accession
PTN1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:4553
GenAtlas
GPX1
GeneCards
GPX1
GenBank Gene Database
Y00433
GenBank Protein Database
577777
UniProt Accession
GPX1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:1516
GenAtlas
CAT
GeneCards
CAT
GenBank Gene Database
X04085
GenBank Protein Database
1228085
UniProt Accession
CATA_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:441
GenAtlas
ALPPL2
GeneCards
ALPG
GenBank Gene Database
J03252
GenBank Protein Database
178428
UniProt Accession
PPBN_HUMAN
Patent information
5 active patents, 1 expired
Source: DrugBank · CC BY-NC 4.0. Patent data sourced from national patent offices. Expiry dates may not reflect extensions, regulatory exclusivity periods, or legal challenges.
DrugBank citations
If you use DrugBank data in your research, please cite the following publications: