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Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing all 21 studies.
Randomised trials: 2 · 2019–2025
Showing all 21 studies, sorted by most relevant.
Divyansh Srivastava, Dr. Charanjeet Singh, D. S. Anand, et al.
EPH-International Journal of Applied Science, 2025
Background-Cervical spondylitis is a prevalent condition among computer operators which causes neck pain due to prolonged sitting, poor posture, and repetitive neck strain. Homoeopathic medicines have shown good results in relieving pain, improving mobility, and enhancing overall well-being in patients with cervical spondylitis, offering a holistic and non-invasive treatment. Aim- To determine homoeopathic medicine can improve the neck pain in daily living in computer operators. Methodology- This clinical interventional study evaluated the effectiveness of individualized homoeopathic treatment in 100 cases of cervical spondylitis among computer operators aged 20–60 years, from the OPD of Sri Ganganagar Homoeopathic Medical College based on defined inclusion and exclusion criteria. Symptoms were assessed using the Neck Disability Index (NDI) before and after treatment. Remedies were prescribed according to homoeopathic principles, and data were analyzed using SPSS version 29 with a paired t-test. Result- A marked reduction in Neck Disability Index scores were noted down, (t99=15.00 with p<0.001 which is greater than its tabulated value 1.98 at 5% level of significance). Clinically, 70% of patients showed significant improvement, while 20% improved moderately. Cocculus indicus was prescribed in maximum cases as indicated remedy, followed by Belladonna and Rhus Toxicodendron. Conclusion- Homoeopathic treatment showed significant improvement in symptoms of cervical spondylitis among computer operators, with a marked reduction in disability and neck pain. These findings support the effectiveness of individualized homoeopathic management, though further randomized controlled trials are recommended.
Abstract licence: CC BY
Megan O'Connell, PharmD, BCPP, Elizabeth Hunt, MD, Amy VandenBerg, PharmD, BCPP
Mental Health Clinician, 2021
OBJECTIVE: To describe a case of a patient who developed psychosis after ingestion of Vertigoheel for treatment of dizziness. CASE SUMMARY: A 28-year-old male with no psychiatric history presented with 5 days of worsening depression and psychosis. He denied current use of prescription medications, alcohol, or illicit substances. Approximately 2 weeks prior, while visiting family in Germany, he developed dizziness. A provider in Germany prescribed Vertigoheel, 1 tablet to be taken every hour until symptom improvement. This did not improve his dizziness but did cause him to feel as if he were "in a dream." He stopped taking the medication after 2 days but continued to feel amotivated with decreased appetite and insomnia. Several days later, he developed ego-dystonic auditory hallucinations. He returned to the United States; was admitted to an inpatient psychiatric unit for 4 days; and given olanzapine 5 mg at bedtime, lorazepam 1 mg every evening, and melatonin 6 mg every evening. He experienced gradual improvement in symptoms and was discharged with olanzapine 5 mg daily and outpatient follow-up. DISCUSSION: , and petroleum. Psychosis was not reported in any of the randomized controlled trials evaluating the use of Vertigoheel for treatment of vertigo. A literature search revealed no published reports of psychosis as a result of administration of any components of Vertigoheel. CONCLUSION: A possible causal relationship was observed between the homeopathic supplement Vertigoheel and an acute episode of psychosis in a young male patient with no comorbidities.
Abstract licence: CC BY-NC
Soto-Sánchez J, Garza-Treviño G
2024
Insomnia is a widespread disease that tends to be associated with other problems, like anxiety. The most frequent anxiety disorder is generalized anxiety disorder (GAD), which is characterized by excessive worrying about everyday situations. Medications for insomnia and anxiety can have adverse reactions and the latter may be ineffective in up to 30% of patients. Here we present a case report of a 27-year-old male patient who suffered from persistent insomnia with comorbid GAD and schizophreniform disorder. Initially, he was taking alprazolam, paroxetine, and risperidone, which had a less-than-satisfactory effect. He was treated with individualized homeopathy, which produced a remarkable improvement within four months. This was evidenced by a decrease in difficulty falling asleep and daytime sleepiness; in addition, anxiety and its accompanying symptoms, such as irritability and diaphoresis, were reduced. This improvement persists for up to one year after the commencement of treatment and despite discontinuation of all medications. This clinical report provides preliminary evidence that persistent insomnia and comorbid GAD can be treated successfully with individualized homeopathy. However, further randomized controlled studies are needed to evaluate its efficacy, effectiveness, and safety more conclusively.
Abstract licence: CC BY
Oxford English Dictionary, 2024
Vademecum Anthroposophische Arzneimittel, 2024
PABLO FERNANDO FELIZ, THIAGO FERNANDES, JOÃO MARCELO ALVARENGA BRAGA
Phytotaxa, 2024
Arun S M, Mohit Sharma, Praveen D V
African Journal of Biomedical Research, 2024
Background: Primary dysmenorrhea is a prevalent menstrual disorder among adolescent and young women, characterized by cramping pain without structural pelvic pathology. The condition results mainly from excessive prostaglandin release, leading to uterine hypercontractility and ischemic pain¹˒². Homoeopathy, based on the principle of individualization, provides a holistic, symptom-specific therapeutic approach³˒⁴. Objective: To evaluate the effectiveness of individualized homoeopathic management in primary dysmenorrhea and assess the causal relationship between prescribed remedies and clinical improvement using the Naranjo Adverse Drug Reaction Probability Scale. Methods: An open-label, descriptive case series was conducted on five unmarried female students aged 17–21 years presenting with primary dysmenorrhea. Detailed case taking was performed, considering mental, physical, and menstrual symptoms. Remedies were selected based on totality of symptoms and administered in 200C potency as a single dose, followed by placebo. Pain intensity was recorded before and after treatment (BT and AT). Causality was assessed using the Naranjo Scale¹². Results: The commonly indicated medicines were Pulsatilla nigricans, Nux vomica, and Cocculus indicus. All patients reported significant reduction in menstrual pain and associated concomitants. Mean BT score was 11.4 and AT score 1.8, indicating an 83.6 % improvement. Naranjo scores (6–8) confirmed a probable causal relationship between the prescribed homoeopathic remedy and observed improvement. No adverse events were reported. Conclusion: Individualized homoeopathic management demonstrated substantial clinical effectiveness in primary dysmenorrhea. The consistent improvement, absence of adverse effects, and supportive Naranjo evaluation highlight the therapeutic potential of homoeopathy as a complementary approach in menstrual pain management. Further controlled multicentric trials are warranted for validation.
Abstract licence: CC BY
Paulo Francisco Maciel Póvoas Souto, Tássia Ferreira- Pires, Pábola Santos Nascimento, et al.
Bioscience Journal, 2019
The aim of this work was to determine the effect of homeopathic supplementation on both ovarian dynamics and conception rate in Nellore cows subjected to fixed-time artificial insemination (FTAI). Cows (n = 150) were randomly distributed to the control (CG) and the homeopathy group (HG). The HG cows were supplemented with Pró-cio in the mineral salt for 60 days and both experimental groups were further subjected to FTAI. Cows were evaluated for ovarian dynamics (n = 16), progesterone (P4) concentration (n = 16), and conception rates (n = 150). Ovarian dynamics determined by ultrasonography and showed similar findings for CG and HG, respectively. Thus follicular diameter (8.7 ± 1.0 mm vs. 10.0 ± 0.8 mm), mean pre-ovulatory follicle volume (0.46 ± 0.15 mL vs. 0.61 ± 0.12 mL), and mean follicular growth (3.65 ± 1.41 mm vs. 4.60 ± 1.21 mm) did not differ between groups. Moreover, corpus luteum diameter was similar between groups (CG: 16.28 ± 0.7 mm vs. HG: 15.6 ± 0.8 mm; P > 0.05), although P4 levels did differ (CG: 2.55 ± 0.85 ng mL-1 vs. HG: 6.52 ± 1.19 ng mL-1; P < 0.05). The conception rate after FTAI was not affected by homeopathic supplementation (CG: 74.67 %, and did HG: 77.33 %; P > 0.05). In conclusion, the homeopathic supplementation Pró-cio increases P4 concentrations but does improve the reproductive efficiency of Nellore cows subject to FTAI.
Abstract licence: CC BY
CABI Compendium, 2019
CABI Compendium, 2019
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Scientific data (pharmacology, interactions, ADME) is not yet available for this medicine. Clinical sections are sourced from the NHS dm+d database.