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Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
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Suspected adverse reactions reported for Borax
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Submit a Yellow Card report to the MHRA
Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.
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EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
1 branded products available
Therapeutically similar medicines
Similarity is based on WHO Anatomical Therapeutic Chemical (ATC) classification and on a factual NHS dm+d therapeutic-grouping code prefix. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.
NHS prescribing volume and spending trends
Check stock at pharmacies and supply information
Pharmacy stock checkers
Search for this medicine at major UK pharmacy chains. These links open the retailer's own website — results depend on their current online catalogue.
Supply & safety information
Official UK regulator monitoring and safety alerts
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. Shortage and safety information sourced from MHRA drug safety updates (gov.uk, Crown Copyright under OGL v3.0).
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF code shown is the factual mapping value distributed by NHS Business Services Authority (NHSBSA) in the dm+d supplementary file under OGL v3.0; it is not affiliated with, nor licensed from, the publishers of the British National Formulary.
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing the 50 most relevant studies.
Reviews & meta-analyses: 3 · 1923–2025
Showing the 50 most relevant studies, sorted by most relevant.
Niels Hadrup, Marie Frederiksen, Anoop Sharma
Regulatory Toxicology and Pharmacology, 2021
- Administration, Cutaneous
- Administration, Inhalation
- Boron Compounds
Seungwan Cho, Sung Yeon Hwang, Dongyeop X. Oh, et al.
Journal of Materials Chemistry A, 2021
Minfeng Chen, Weijun Zhou, Anran Wang, et al.
Journal of Materials Chemistry A, 2020
Beili Lu, Fengcai Lin, Xin Jiang, et al.
ACS Sustainable Chemistry & Engineering, 2016
Minfeng Chen, Jizhang Chen, Weijun Zhou, et al.
Journal of Materials Chemistry A, 2019
Jingquan Han, Yiying Yue, Qinglin Wu, et al.
Cellulose, 2017
Katherine Warington
Annals of Botany, 1923
Steven Spoljaric, Arto Salminen, Nguyen Dang Luong, et al.
European Polymer Journal, 2014
R. J. Weir, Russell S. Fisher
Toxicology and Applied Pharmacology, 1972
- Body Weight
- Borates
- Boric Acids
Jingquan Han, Tingzhou Lei, Qinglin Wu
Carbohydrate Polymers, 2013
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
None known
Half-life
13 to 24 hours
Mechanism
Information regarding the mechanism of action of boric acid in mediating its ant…
Food interactions
None known
Human targets
None mapped
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Absorption
1.0-1.5 hr
[L2140]…
Half-life
13 to 24 hours
[A32450][L2140]
Protein binding
Volume of distribution
0.17 to 0.5 L/kg
[L2140]
Metabolism
Elimination
90%
Clearance
0.99 L/h
Pharmacokinetic data: DrugBank · CC BY-NC 4.0
[L14450]
Individuals are likely to be exposed to boric acid from industrial manufacturing or processing. Local tissue injury from boric acid exposure is likely due to caustic effects. Systemic effects from boric acid poisoning usually occur from multiple exposures over a period of days and involve gastrointestinal, dermal, CNS, and renal manifestations.
Gastrointestinal toxicity include persistent nausea, vomiting, diarrhea, epigastric pain, hematemesis, and blue-green discoloration of the feces and vomit .
[L2140]
Following the onset of GI symptoms, a characteristic intense generalized erythroderma follows .
[L2140]
Management of mild to moderate toxicity should be supportive. In case of severe toxicity, dialysis may be required in addition to supportive treatment.
How the body processes this drug — absorption, distribution, metabolism, and elimination
[L2140]
Following intraperitoneal injection in mice, the peak concentration was reached in about 1.0-1.5 hr in the brain whereas the value was 0.5 hr in other tissues .
[L2140]
[A32450][L2140]
[L2140]
[L2140]
[A32450]
ATC S01AX07
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
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Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Linked compound data from DrugBank Open Data (CC BY-NC 4.0)
Sodium borate
Matched from: Borax
DrugBank citations
If you use DrugBank data in your research, please cite the following publications:
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Structured knowledge from the free knowledge base
Linked open data from Wikidata (Q27118021), a free and open knowledge base operated by the Wikimedia Foundation. Data is available under the Creative Commons CC0 1.0 Public Domain Dedication.