Borax powder

The acute oral LD₅₀ in rats is 4500-5000 mg/kg and the intradermal LD₅₀ in rabbits is 10,000 mg/kg.
[L14450]
Individuals are likely to be exposed to boric acid from industrial manufacturing or processing. Local tissue injury from boric acid exposure is likely due to caustic effects. Systemic effects from boric acid poisoning usually occur from multiple exposures over a period of days and involve gastrointestinal, dermal, CNS, and renal manifestations.

Gastrointestinal toxicity include persistent nausea, vomiting, diarrhea, epigastric pain, hematemesis, and blue-green discoloration of the feces and vomit .
[L2140]
Following the onset of GI symptoms, a characteristic intense generalized erythroderma follows .
[L2140]
Management of mild to moderate toxicity should be supportive. In case of severe toxicity, dialysis may be required in addition to supportive treatment.