Zinc sulfate 50micromol/1ml solution for injection ampoules
Requires a prescription from a doctor or prescriber
Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol".
Official documents, adverse reaction reporting, and safety monitoring
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Official medicine documents
Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
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Suspected adverse reactions reported for Zinc sulfate
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Submit a Yellow Card report to the MHRA
Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.
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Suspected adverse reactions reported for Zinc sulfate
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EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
1 branded products available
Therapeutically similar medicines
Similarity is based on WHO Anatomical Therapeutic Chemical (ATC) classification and on a factual NHS dm+d therapeutic-grouping code prefix. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.
Check stock at pharmacies and supply information
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Search for this medicine at major UK pharmacy chains. These links open the retailer's own website — results depend on their current online catalogue.
Supply & safety information
Official UK regulator monitoring and safety alerts
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. Shortage and safety information sourced from MHRA drug safety updates (gov.uk, Crown Copyright under OGL v3.0).
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
Browse tools
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF code shown is the factual mapping value distributed by NHS Business Services Authority (NHSBSA) in the dm+d supplementary file under OGL v3.0; it is not affiliated with, nor licensed from, the publishers of the British National Formulary. ATC codes from the WHO Collaborating Centre for Drug Statistics Methodology (whocc.no).
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing the 50 most relevant studies.
Reviews & meta-analyses: 7 · Randomised trials: 17 · 1967–2026
Showing the 50 most relevant studies, sorted by most relevant.
Wai Yee Wong, Hans M.W.M. Merkus, Chris M.G. Thomas, et al.
Fertility and Sterility, 2002
- Folic Acid
- Infertility, Male
- Semen
Shahin Akhondzadeh, Mohammad-Reza Mohammadi, Mojgan Khademi
BMC Psychiatry, 2004
- Ambulatory Care
- Attention Deficit Disorder with Hyperactivity
- Methylphenidate
Carla Ripamonti, Ernesto Zecca, Cinzia Brunelli, et al.
Cancer, 1998
- Combined Modality Therapy
- Evaluation Studies as Topic
- Head and Neck Neoplasms
de Oliveira HM, Gallo Ruelas M, Barbosa LM, et al.
2024
- Zinc Sulfate
- Phototherapy
- Hyperbilirubinemia, Neonatal
Ghadirzadeh B, Afshar M, Afraie M, et al.
2025
- Zinc Sulfate
- Dietary Supplements
- Hyperbilirubinemia, Neonatal
Sayed MS, Rath S, Hermis AH, et al.
2026
Li Yang, De Wu, Baotian Wang, et al.
The Journal of Maternal-Fetal & Neonatal Medicine, 2018
X. Tian, Xiao-Ling Liu, Yuan-Ping Pi, et al.
Frontiers in Oncology, 2018
Lorenzo Rossi, Lauren Fedenia, Hamidreza Sharifan, et al.
Plant Physiology and Biochemistry, 2018
- Chlorophyll
- Microscopy, Electron, Scanning
- Photosynthesis
Hao Chen, Chunlong Dai, Fangyuan Xiao, et al.
Advanced Materials, 2022
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
None known
Half-life
3 hours
Mechanism
Zinc inhibits cAMP-induced, chloride-dependent fluid secretion by inhibiting bas…
Food interactions
3 warnings
Human targets
None mapped
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Absorption
20 to 30%
Half-life
3 hours
Protein binding
60%
Volume of distribution
Elimination
90%
Pharmacokinetic data: DrugBank · CC BY-NC 4.0
Known interactions with other medications. Always consult a healthcare professional.
Showing 50 of 62 interactions
Human: TDLo (oral) 106mg/kg : Hypermotylity, diarrhea
Mouse ; LD50 Oral : 245mg/kg
Mouse : LD50 : subcutaneous : 781mg/kg
How the body processes this drug — absorption, distribution, metabolism, and elimination
Phytates may impair absorption by chelation and formation of insoluble complexes at an alkaline pH. After absorption, zinc is bound in the intestine to the protein metallothionein. Endogenous zinc can be reabsorbed in the ileum and colon, creating an enteropancreatic circulation of zinc.
ATC C05AX04
ATC A12CB01
ATC B05XA18
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
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Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Linked compound data from DrugBank Open Data (CC BY-NC 4.0)
Zinc sulfate
DrugBank citations
If you use DrugBank data in your research, please cite the following publications:
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Structured knowledge from the free knowledge base
Molecular structure
ATC classifications (Wikidata)
Linked open data from Wikidata (Q204954), a free and open knowledge base operated by the Wikimedia Foundation. Data is available under the Creative Commons CC0 1.0 Public Domain Dedication. Molecular structure images from Wikimedia Commons.