Ubidecarenone 30mg / Magnesium oxide 150mg tablets

Wastewater contamination by heavy metals and synthetic dyes presents a significant environmental challenge, necessitating effective and sustainable separation techniques. This review article provides a detailed examination of magnesium oxide (MgO) nanoparticles as an innovative nanoadsorbent for wastewater treatment, with a specific focus on heavy metal and dye removal. The review comprehensively explores various aspects of MgO nanoparticles, including their structural characteristics and synthesis techniques. The article delves into the morphology and crystallographic arrangement of MgO nanoparticles, offering insights into their structural attributes. Given the complexity of adsorption processes, the review identifies and analyzes parameters influencing the adsorption efficiency of MgO nanoparticles, such as temperature, pH, contact time, initial concentration, and co-existing ions. The interplay between these parameters and the adsorption capability of MgO nanoparticles emphasizes the importance of optimizing operational conditions. Furthermore, the review assesses various synthesis methods for MgO nanoparticles, including sol-gel, hydrothermal, precipitation, green synthesis, solvothermal, and template-assisted techniques. It discusses the advantages, limitations, and resulting nanoparticle characteristics of each method, enabling readers to grasp the implications of synthesis processes on adsorption efficiency. This comprehensive review consolidates current insights into the effectiveness of MgO nanoparticles as a potent nanoadsorbent for removing heavy metals and dyes from wastewater covering a wide spectrum of aspects related to MgO nanoparticles. Moreover, there is a need to investigate the use of MgO in the treatment of actual wastewater or river water, in order to leverage its cost-effectiveness and high efficiency for practical water treatment applications in real-time.

Abstract licence: CC BY-NC-ND

In recent times, there has been considerable interest among researchers in magnesium oxide (MgO) nanoparticles, due to their excellent biocompatibility, stability, and diverse biomedical uses, such as antimicrobial, antioxidant, anticancer, and antidiabetic properties, as well as tissue engineering, bioimaging, and drug delivery applications. Consequently, the escalating utilization of magnesium oxide nanoparticles in medical contexts necessitates the in-depth exploration of these nanoparticles. Notably, existing literature lacks a comprehensive review of magnesium oxide nanoparticles’ synthesis methods, detailed biomedical applications with mechanisms, and toxicity assessments. Thus, this review aims to bridge this gap by furnishing a comprehensive insight into various synthetic approaches for the development of MgO nanoparticles. Additionally, it elucidates their noteworthy biomedical applications as well as their potential mechanisms of action, alongside summarizing their toxicity profiles. This article also highlights challenges and future prospects for further exploring MgO nanoparticles in the biomedical field. Existing literature indicates that synthesized magnesium oxide nanoparticles demonstrate substantial biocompatibility and display significant antibacterial, antifungal, anticancer, and antioxidant properties. Consequently, this review intends to enhance readers’ comprehension regarding recent advancements in synthesizing MgO nanoparticles through diverse approaches and their promising applications in biomedicine.

Abstract licence: CC BY

Magnesium (Mg) is considered an attractive option for orthopedic applications due to its density and elastic modulus close to the natural bone of the body, as well as biodegradability and good tensile strength. However, it faces serious challenges, including a high degradation rate and, as a result, a loss of mechanical properties during long periods of exposure to the biological environment. Also, among its other weaknesses, it can be mentioned that it does not deal with bacterial biofilms. It has been found that making composites by synergizing its various components can be an efficient way to improve its properties. Among metal oxide nanoparticles, magnesium oxide nanoparticles (MgO NPs) have distinct physicochemical and biological properties, including biocompatibility, biodegradability, high bioactivity, significant antibacterial properties, and good mechanical properties, which make it a good choice as a reinforcement in composites. However, the lack of comprehensive understanding of the effectiveness of Mg NPs as Mg matrix reinforcements in mechanical, corrosion, and biological fields is considered a challenge in their application. While introducing the role of MgO NPs in medical fields, this article summarizes the most important results of recent research on the mechanical, corrosion, and biological performance of Mg/MgO composites.

Abstract licence: CC BY

Herein, the metabolites secreted by brown algae, Cystoseira crinita , were used as biocatalyst for green synthesis of magnesium oxide nanoparticles (MgO-NPs). The fabricated MgO-NPs were characterized using UV-vis spectroscopy, Fourier transforms infrared spectroscopy (FT-IR), Transmission Electron Microscopy (TEM), Scanning Electron Microscopy linked with energy-dispersive X-ray (SEM-EDX), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). Data showed successful formation of crystallographic and spherical MgO-NPs with sizes of 3–18 nm at a maximum surface plasmon resonance of 320 nm. Moreover, EDX analysis confirms the presence of Mg and O in the sample with weight percentages of 54.1% and 20.6%, respectively. Phyco-fabricated MgO-NPs showed promising activities against Gram-positive bacteria, Gram-negative bacteria, and Candida albicans with MIC values ranging between 12.5 and 50 μg mL −1 . The IC 50 value of MgO-NPs against cancer cell lines (Caco-2) was 113.4 μg mL −1 , whereas it was 141.2 μg mL −1 for normal cell lines (Vero cell). Interestingly, the green synthesized MgO-NPs exhibited significant larvicidal and pupicidal activity against Musca domestica. At 10 μg mL −1 MgO-NPs, the highest mortality percentages were 99.0%, 95.0%, 92.2%, and 81.0% for I, II, III instars’ larvae, and pupa of M. domestica , respectively, with LC 50 values (3.08, 3.49, and 4.46 μg mL −1 ), and LC 90 values (7.46, 8.89, and 10.43 μg mL −1 ), respectively. Also, MgO-NPs showed repellence activity for adults of M. domestica at 10 μg mL −1 with 63.0%, 77.9%, 84.9%, and 96.8% after 12, 24, 48, and 72 h, respectively.

Abstract licence: CC BY

People are vulnerable to mosquito-borne infections in tropical and subtropical climate countries. Due to resistive issues, vector control is an immediate concern in today’s environment. The current study describes the synthesis of magnesium oxide by four different approaches including green, microwave, sol–gel, and hydrothermal methods. The synthesized magnesium oxide (MgO) nanoparticles were characterized using Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), high-resolution scanning electron microscopy (HRSEM), and energy-dispersive X-ray analysis (EDAX) techniques. The FT-IR studies reveal the presence of functional groups in the synthesized nanoparticles. The structural and morphological studies were investigated using XRD and HRSEM. EDAX reveals the presence of Mg and O in the prepared samples. The synthesized MgO NPs were screened for antibacterial studies against Gram-positive strains, Enterococcus faecalis and Staphylococcus aureus, two Gram-negative cultures, Escherichia coli and Klebsiella pneumoniae, using different concentrations. The results indicated excellent antibacterial activity against both Gram-positive and Gram-negative bacteria at 50 mg/mL hydrothermally produced MgO nanoparticles, with a maximal zone of inhibition (ZOI) of 5 mm for S. aureus, 7 mm for E. faecalis, and 6 mm for K. pneumoniae. The ZOI of E. coli was found to be the greatest at 9 mm when 50 mg/mL sol–gel-produced MgO nanoparticles were used. The synthesized MgO nanostructures were tested against fourth-instar larvae of Aedes aegypti and Aedes albopictus, and the hydrothermally synthesized MgO nanostructures exhibited better results when compared with other methods of synthesis. The reports show that A. aegypti and A. albopictus mortality rates were reported to be the lowest with green-manufactured MgO nanoparticles (7.5 g mL–1) and the highest with hydrothermally synthesized MgO nanoparticles (120 g mL–1). The research indicates that MgO nanostructures are promising drugs for antibacterial and mosquitocidal larvae control properties.

Abstract licence: CC BY-NC-ND

A five-layered Kretschmann configuration-based novel structure is designed for a highly sensitive surface plasmon resonance (SPR) sensor. An adhesion layer of magnesium oxide (MgO) is employed on the BK7 prism to avoid the adverse effects of metallic layers, which cause SPR broadening and a decrease in the resonance magnitude. A few layers of black phosphorus (BP) on top of the silver (Ag) metal layer are added to complete the structure, which becomes the BK7/MgO/Ag/BP configuration. The investigation is carried out using attenuated total reflection (ATR), while the widely used transfer matrix method (TMM) is applied to evaluate the performance of the SPR sensor. A separate analysis is performed using three thicknesses, 5 nm, 10 nm, and 15 nm of MgO, an optimized thickness of 40 nm of Ag, and eight layers of BP. The results revealed that the configuration BK7/MgO (10 nm)/Ag (40 nm)/BP (8 layers) delivers a maximum sensitivity (S) of 234°RIU −1 . Moreover, the configuration BK7/MgO (5 nm)/Ag (40 nm)/BP (8 layers) delivers a maximum figure of merit (FOM) of 38.18°RIU −1 . With these kinds of extraordinary features, it is expected that the proposed SPR sensor can be applied in different fields of biosensing.

Abstract licence: CC BY