Sucrose 24% oral drops
A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.
Official documents, adverse reaction reporting, and safety monitoring
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Official medicine documents
Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
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Suspected adverse reactions reported for Sucrose
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Submit a Yellow Card report to the MHRA
Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.
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Suspected adverse reactions reported for Sucrose
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EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
1 branded products available
Guidelines from the National Institute for Health and Care Excellence
NICE clinical guidance(5)
Chronic heart failure in adults: diagnosis and management (NG106)
Chronic kidney disease: assessment and management (NG203)
End of life care for infants, children and young people with life-limiting conditions: planning and management (NG61)
Dementia, disability and frailty in later life – mid-life approaches to delay or prevent onset (NG16)
Type 2 diabetes in adults: management (NG28)
Source: National Institute for Health and Care Excellence (NICE). Contains public sector information licensed under the Open Government Licence v3.0.
Check stock at pharmacies and supply information
Pharmacy stock checkers
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Supply & safety information
Official UK regulator monitoring and safety alerts
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. Shortage and safety information sourced from MHRA drug safety updates (gov.uk, Crown Copyright under OGL v3.0).
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF code shown is the factual mapping value distributed by NHS Business Services Authority (NHSBSA) in the dm+d supplementary file under OGL v3.0; it is not affiliated with, nor licensed from, the publishers of the British National Formulary.
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing all 30 studies.
Reviews & meta-analyses: 11 · Randomised trials: 1 · 2004–2022
Showing all 30 studies, sorted by most relevant.
M. Edmonds, J. Lázaro-Martínez, Jesús Alfayate-García, et al.
The lancet. Diabetes & endocrinology, 2017
- Bandages
- Anti-Ulcer Agents
- Diabetic Neuropathies
O. Stein, D. Granot
Frontiers in Plant Science, 2019
Sucrose is the end product of photosynthesis and the primary sugar transported in the phloem of most plants. Sucrose synthase (SuSy) is a glycosyl transferase enzyme that plays a key role in sugar metabolism, primarily in sink tissues. SuSy catalyzes the reversible cleavage of sucrose into fructose and either uridine diphosphate glucose (UDP-G) or adenosine diphosphate glucose (ADP-G). The products of sucrose cleavage by SuSy are available for many metabolic pathways, such as energy production, primary-metabolite production and the synthesis of complex carbohydrates. SuSy proteins are usually homotetramers with an average monomeric molecular weight of about 90 kD (about 800 amino acids long). Plant SuSy isozymes are mainly located in the cytosol and plasma membrane, but some SuSy proteins are found in the cell wall, vacuoles and mitochondria. Plant SUS gene families are usually small, containing between four to seven genes, with distinct exon-intron structures. Plant SUS genes are divided into three separate clades, which are present in both monocots and dicots. A comprehensive phylogenetic analysis indicates that a first SUS duplication event may have occurred before the divergence of the gymnosperms and angiosperms and a second duplication event probably occurred in a common angiosperm ancestor, leading to the existence of all three clades in both monocots and dicots. Plants with reduced SuSy activity have been shown to have reduced growth, reduced starch, cellulose or callose synthesis, reduced tolerance to anaerobic-stress conditions and altered shoot apical meristem function and leaf morphology. Plants overexpressing SUS have shown increased growth, increased xylem area and xylem cell-wall width, and increased cellulose and starch contents, making SUS high-potential candidate genes for the improvement of agricultural traits in crop plants. This review summarizes the current knowledge regarding plant SuSy, including newly discovered possible developmental roles for SuSy in meristem functioning that involve sugar and hormonal signaling.
Abstract licence: CC BY
Jinmi Yoon, Lae-Hyeon Cho, Win Tun, et al.
Plant science : an international journal of experimental plant biology, 2021
- Signal Transduction
- Plants
- Sucrose
H. Wan, Limin Wu, Yuejian Yang, et al.
Trends in plant science, 2017
- Biological Evolution
- Phylogeny
- Plant Proteins
Katharina Schmölzer, Alexander Gutmann, Margo Diricks, et al.
Biotechnology advances, 2016
- Glucosyltransferases
- Glycosylation
- Bacterial Proteins
B. Stevens, J. Yamada, A. Ohlsson, et al.
The Cochrane database of systematic reviews, 2016
K. Koch
Current opinion in plant biology, 2004
- Plant Development
- Glucosyltransferases
- Plants
Yong-ling Ruan
Annual review of plant biology, 2014
- Biological Transport
- Plants
- Sucrose
D. Braun
Annual review of plant biology, 2022
- Sucrose
- Phloem
- Biological Transport
W. Marques, V. Raghavendran, B. Stambuk, et al.
FEMS yeast research, 2016
- Ethanol
- Biotechnology
- Brazil
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
None known
Half-life
Not available
Mechanism
Not available
Food interactions
None known
Human targets
5 targets
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Proteins and enzymes this drug interacts with in the body
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
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Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Linked compound data from DrugBank Open Data (CC BY-NC 4.0)
Sucrose
Additional database identifiers
Drugs Product Database (DPD)
8818
ChemSpider
5768
BindingDB
50108105
ZINC
ZINC000004217475
GenBank Gene Database
X04121
GenBank Protein Database
581568
UniProt Accession
BLAC_STAAU
HUGO Gene Nomenclature Committee (HGNC)
HGNC:14905
GenAtlas
TAS1R2
GeneCards
TAS1R2
GenBank Gene Database
AF458154
GenBank Protein Database
20142333
UniProt Accession
TS1R2_HUMAN
GenBank Gene Database
J01611
GenBank Protein Database
145267
UniProt Accession
AMPC_ECOLI
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6740
GeneCards
LYZ
UniProt Accession
LYSC_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:129
GenAtlas
ACTA1
GeneCards
ACTA1
GenBank Gene Database
J00068
GenBank Protein Database
178029
UniProt Accession
ACTS_HUMAN
GenBank Gene Database
AJ011781
UniProt Accession
AMYS_NEIPO
GenBank Gene Database
AF252621
UniProt Accession
Q9L5C8_ECOLX
UniProt Accession
Q939N4_ECOLX
UniProt Accession
Q9L5C7_ECOLX
UniProt Accession
Q840M4_ECOLX
GenBank Gene Database
U73860
UniProt Accession
HMUO_CORDI
HUGO Gene Nomenclature Committee (HGNC)
HGNC:798
GenAtlas
ATOX1
GeneCards
ATOX1
GenBank Gene Database
U70660
UniProt Accession
ATOX1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:26935
GeneCards
RTCB
UniProt Accession
RTCB_HUMAN
UniProt Accession
OCP_LIMMA
GenBank Gene Database
X57400
UniProt Accession
SCRY_SALTM
GenBank Gene Database
Z94043
UniProt Accession
LSC_BACSU
DrugBank citations
If you use DrugBank data in your research, please cite the following publications:
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Structured knowledge from the free knowledge base
Linked open data from Wikidata (Q4027534), a free and open knowledge base operated by the Wikimedia Foundation. Data is available under the Creative Commons CC0 1.0 Public Domain Dedication.