Sodium chloride 0.9% solution for injection 50ml vials
Requires a prescription from a doctor or prescriber
Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions.
Official documents, adverse reaction reporting, and safety monitoring
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Official medicine documents
Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
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Suspected adverse reactions reported for Sodium chloride
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Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
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Suspected adverse reactions reported for Sodium chloride
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EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
3 branded products available
Part of the Knoxzy brand family (generic: Sodium chloride)
MHRA licensed products
View all licensed products for Sodium chloride on the MHRA register
Sodium chloride 0.9% solution for injection 50ml vials
Sodium chloride 0.9% solution for injection 50ml vials
This is the NHS Drug Tariff indicative price used for reimbursement purposes. It may not reflect the price paid by patients or pharmacies.
View full Drug TariffSource: NHS Drug Tariff via NHSBSA. Derived from dm+d VMPP (Virtual Medicinal Product Pack) pricing data. Contains public sector information licensed under the Open Government Licence v3.0.
Therapeutically similar medicines
Similarity is based on WHO Anatomical Therapeutic Chemical (ATC) classification and on a factual NHS dm+d therapeutic-grouping code prefix. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.
NHS prescribing volume and spending trends
Guidelines from the National Institute for Health and Care Excellence
NICE clinical guidance(13)
Intravenous fluid therapy in children and young people in hospital (NG29)
Diarrhoea and vomiting caused by gastroenteritis in under 5s: diagnosis and management (CG84)
Intravenous fluid therapy in adults in hospital (CG174)
Intravenous fluid therapy in children and young people in hospital (QS131)
Cystic fibrosis: diagnosis and management (NG78)
Diabetes (type 1 and type 2) in children and young people: diagnosis and management (NG18)
Adrenal insufficiency: identification and management (NG243)
Neonatal parenteral nutrition (NG154)
Intravenous fluid therapy in adults in hospital (QS66)
Constipation in children and young people: diagnosis and management (CG99)
Acute kidney injury: prevention, detection and management (NG148)
Mexiletine for treating the symptoms of myotonia in non-dystrophic myotonic disorders (TA748)
Healthcare-associated infections: prevention and control in primary and community care (CG139)
Source: National Institute for Health and Care Excellence (NICE). Contains public sector information licensed under the Open Government Licence v3.0.
Check stock at pharmacies and supply information
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Supply & safety information
Official UK regulator monitoring and safety alerts
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. Shortage and safety information sourced from MHRA drug safety updates (gov.uk, Crown Copyright under OGL v3.0).
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
Browse tools
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF code shown is the factual mapping value distributed by NHS Business Services Authority (NHSBSA) in the dm+d supplementary file under OGL v3.0; it is not affiliated with, nor licensed from, the publishers of the British National Formulary. ATC codes from the WHO Collaborating Centre for Drug Statistics Methodology (whocc.no).
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing the 50 most relevant studies.
Reviews & meta-analyses: 2 · Randomised trials: 7 · 1940–2026
Showing the 50 most relevant studies, sorted by most relevant.
T. J. Flowers, Rana Munns, Timothy D. Colmer
Annals of Botany, 2014
- Salt Tolerance
- Sodium Chloride
- Stress, Physiological
John M. Russell
Physiological Reviews, 2000
- Carrier Proteins
- Cell Membrane
- Chlorides
Zhenguo Shi, Mette Rica Geiker, Barbara Lothenbach, et al.
Cement and Concrete Composites, 2017
Samantha K. Trumbo, Michael E. Brown, K. P. Hand
Science Advances, 2019
S. Weisbord, M. Gallagher, H. Jneid, et al.
The New England Journal of Medicine, 2017
Nathalie Busschaert, Seong H Park, Kyung-Hwa Baek, et al.
Nature chemistry, 2017
Hao-bo Sun, Guanzhou Zhu, Xintong Xu, et al.
Nature Communications, 2019
E. Adolph, Birgit Holdt-Lehmann, T. Chatterjee, et al.
Coronary Artery Disease, 2008
T. Klima, A. Christ, I. Marana, et al.
European heart journal, 2012
K. D. Weerdt, B. Lothenbach, M. Geiker
Cement and Concrete Research, 2019
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
None known
Half-life
17 minutes
Mechanism
Sodium and chloride — major electrolytes of the fluid compartment outside of cells (i.
Food interactions
None known
Human targets
None mapped
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Absorption
Half-life
17 minutes
Protein binding
Volume of distribution
0.64 L/kg
Metabolism
Elimination
Pharmacokinetic data: DrugBank · CC BY-NC 4.0
Known interactions with other medications. Always consult a healthcare professional.
Showing 6 of 6 interactions
Chloride, the major extracellular anion, closely follows the metabolism of sodium, and changes in the acid-base balance of the body are reflected by changes in the chloride concentration.
How the body processes this drug — absorption, distribution, metabolism, and elimination
Body maintains an equilibrium retaining the 300gm of salt dissolved in the blood and fluid elements of the tissue dissociated into sodium ions and chloride ions.
ATC B05XA03
ATC B05CB01
ATC A12CA01
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
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Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Linked compound data from DrugBank Open Data (CC BY-NC 4.0)
Sodium chloride
Additional database identifiers
DrugBank citations
If you use DrugBank data in your research, please cite the following publications:
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Structured knowledge from the free knowledge base
Wikipedia article
electrolyte solution for infusion to treat low blood pressure or low blood volume
Read on WikipediaMolecular structure
ATC classifications (Wikidata)
Linked open data from Wikidata (Q2920739), a free and open knowledge base operated by the Wikimedia Foundation. Data is available under the Creative Commons CC0 1.0 Public Domain Dedication. Molecular structure images from Wikimedia Commons.