Sodium bicarbonate 52.5mg/5ml / Terpeneless dill seed oil 2.3mg/5ml oral solution sugar free

This meta-analysis explored the effects of sodium bicarbonate supplementation on swimming performance. Seven databases were searched to find relevant studies. A random-effects meta-analysis of standardized mean differences (SMD) was performed to analyze the data. Nine studies were included in the review. There was no significant difference between placebo and sodium bicarbonate when considering data from all included studies (SMD: –0.10; p = 0.208) or in the subgroup analysis for 91.4-m and 100-m swimming tests (SMD: 0.11; p = 0.261). In the subgroup analysis for 200-m and 400-m swimming tests, there was a significant ergogenic effect of sodium bicarbonate (SMD: –0.22; p < 0.001). Overall, these results suggest that sodium bicarbonate ingestion improves performance in 200-m and 400-m swimming events. The ergogenic effects of this supplement were small, but they may also be of substantial practical importance given that placings in swimming competitions are commonly determined by narrow margins.

Abstract licence: CC BY 4.0

PurposeThe purpose of this paper is to review the physiological mechanisms determining eccrine sweat composition to assess the utility of sweat as a proxy for blood or as a potential biomarker of human health or nutritional/physiological status.MethodsThis narrative review includes the major sweat electrolytes (sodium, chloride, and potassium), other micronutrients (e.g., calcium, magnesium, iron, copper, zinc, vitamins), metabolites (e.g., glucose, lactate, ammonia, urea, bicarbonate, amino acids, ethanol), and other compounds (e.g., cytokines and cortisol).ResultsIon membrane transport mechanisms for sodium and chloride are well established, but the mechanisms of secretion and/or reabsorption for most other sweat solutes are still equivocal. Correlations between sweat and blood have not been established for most constituents, with perhaps the exception of ethanol. With respect to sweat diagnostics, it is well accepted that elevated sweat sodium and chloride is a useful screening tool for cystic fibrosis. However, sweat electrolyte concentrations are not predictive of hydration status or sweating rate. Sweat metabolite concentrations are not a reliable biomarker for exercise intensity or other physiological stressors. To date, glucose, cytokine, and cortisol research is too limited to suggest that sweat is a useful surrogate for blood.ConclusionFinal sweat composition is not only influenced by extracellular solute concentrations, but also mechanisms of secretion and/or reabsorption, sweat flow rate, byproducts of sweat gland metabolism, skin surface contamination, and sebum secretions, among other factors related to methodology. Future research that accounts for these confounding factors is needed to address the existing gaps in the literature.

Abstract licence: CC BY