Sodium benzoate 800mg/5ml oral solution
Requires a prescription from a doctor or prescriber
Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions.
Official documents, adverse reaction reporting, and safety monitoring
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Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
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Submit a Yellow Card report to the MHRA
Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.
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EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
1 branded products available
Therapeutically similar medicines
Similarity is based on WHO Anatomical Therapeutic Chemical (ATC) classification and on a factual NHS dm+d therapeutic-grouping code prefix. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.
NHS prescribing volume and spending trends
Check stock at pharmacies and supply information
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Search for this medicine at major UK pharmacy chains. These links open the retailer's own website — results depend on their current online catalogue.
Supply & safety information
Official UK regulator monitoring and safety alerts
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. Shortage and safety information sourced from MHRA drug safety updates (gov.uk, Crown Copyright under OGL v3.0).
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
Browse tools
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF code shown is the factual mapping value distributed by NHS Business Services Authority (NHSBSA) in the dm+d supplementary file under OGL v3.0; it is not affiliated with, nor licensed from, the publishers of the British National Formulary. ATC codes from the WHO Collaborating Centre for Drug Statistics Methodology (whocc.no).
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing the 50 most relevant studies.
Reviews & meta-analyses: 12 · Randomised trials: 12 · 1991–2026
Showing the 50 most relevant studies, sorted by most relevant.
Joseph D. Piper, Peter W. Piper
Comprehensive Reviews in Food Science and Food Safety, 2017
S Sushma, Srinivasan Dasarathy, Rakesh Tandon, et al.
Hepatology, 1992
- Acute Disease
- Benzoates
- Brain
Chieh‐Hsin Lin, Ching-Hua Lin, Yue-Cune Chang, et al.
Biological Psychiatry, 2017
- Clozapine
- Cognition
- D-Amino-Acid Oxidase
Liang CW, Cheng HY, Tseng MM
2024
Mansour MEM, Ali AHG, Ibrahim MHM, et al.
2025
- Alzheimer Disease
- Sodium Benzoate
- Cognition
van Zoest D, Gal B, Agha AH, et al.
2025
- Hepatic Encephalopathy
- Sodium Benzoate
- Hyperammonemia
Axel Wibbertmann
World Health Organization eBooks, 2000
The results of this meta-analysis showed that the pooled sensitivity and the AUC of both the senior and junior radiologist groups were high, with good diagnostic efficacy and high clinical application. However, the results of this study are highly heterogeneous and need to be validated by collecting more high-quality studies and accumulating a larger sample size.
Abstract licence: CC BY-NC-ND
Jyothsna Chinnapura Seetharam, R. Maiti, A. Mishra, et al.
Asian journal of psychiatry, 2021
- Sodium Benzoate
- Schizophrenia
- Oxidoreductases
Yeh PY, Liao RM, Chang HY, et al.
2026
Łucja Justyna Walczak, Mariola Herbet
Nutrients, 2022
- Autism Spectrum Disorder
- Depressive Disorder, Major
- Major Depressive Disorder
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
None known
Half-life
17 minutes
Mechanism
Sodium and chloride — major electrolytes of the fluid compartment outside of cells (i.
Food interactions
None known
Human targets
None mapped
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Absorption
Half-life
17 minutes
Protein binding
Volume of distribution
0.64 L/kg
Metabolism
Elimination
Pharmacokinetic data: DrugBank · CC BY-NC 4.0
Known interactions with other medications. Always consult a healthcare professional.
Showing 6 of 6 interactions
Chloride, the major extracellular anion, closely follows the metabolism of sodium, and changes in the acid-base balance of the body are reflected by changes in the chloride concentration.
How the body processes this drug — absorption, distribution, metabolism, and elimination
Body maintains an equilibrium retaining the 300gm of salt dissolved in the blood and fluid elements of the tissue dissociated into sodium ions and chloride ions.
ATC B05XA03
ATC B05CB01
ATC A12CA01
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
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Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Linked compound data from DrugBank Open Data (CC BY-NC 4.0)
Sodium chloride
Matched from: Sodium benzoate
Additional database identifiers
DrugBank citations
If you use DrugBank data in your research, please cite the following publications:
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Structured knowledge from the free knowledge base
Molecular structure
ATC classifications (Wikidata)
Linked open data from Wikidata (Q423971), a free and open knowledge base operated by the Wikimedia Foundation. Data is available under the Creative Commons CC0 1.0 Public Domain Dedication. Molecular structure images from Wikimedia Commons.