Ritodrine 10mg tablets
Adrenergic beta-agonist used to control premature labor.
Official documents, adverse reaction reporting, and safety monitoring
Report a side effect
Submit a Yellow Card report to the MHRA
Official medicine documents
Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
View Drug Analysis Profile
Suspected adverse reactions reported for Ritodrine
Browse all iDAP reports
Interactive Drug Analysis Profiles for all medicines
Report a side effect
Submit a Yellow Card report to the MHRA
Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.
View EudraVigilance report
Suspected adverse reactions reported for Ritodrine
About EudraVigilance
Learn about EU pharmacovigilance and safety monitoring
EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
1 branded products available
WHO defined daily dose (DDD)
40 mg
Not a recommended dose. The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. It is a statistical measure used for research and comparison purposes only.
Source: WHO Collaborating Centre for Drug Statistics Methodology, distributed via NHS dm+d BNF mapping files. Contains public sector information licensed under the Open Government Licence v3.0.
Therapeutically similar medicines
Similarity based on WHO Anatomical Therapeutic Chemical (ATC) classification and NHS BNF section grouping. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.
NHS prescribing volume and spending trends
Clinical guidelines and formulary information
British National Formulary
Ritodrine
Source: British National Formulary, NICE. Joint Formulary Committee. Contains public sector information licensed under the Open Government Licence v3.0.
Check stock at pharmacies and supply information
Pharmacy stock checkers
Search for this medicine at major UK pharmacy chains. These links open the retailer's own website — results depend on their current online catalogue.
Supply & product information
Official product databases and supply status monitoring
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. emc (electronic medicines compendium) is operated by Datapharm Ltd. Shortage information sourced from NHS Specialist Pharmacy Service (SPS), sps.nhs.uk.
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
Browse tools
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF codes from NHS Business Services Authority (NHSBSA). ATC codes from the WHO Collaborating Centre for Drug Statistics Methodology (whocc.no).
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
None known
Half-life
1.7-2.6 hours
Mechanism
Ritodrine is beta-2 adrenergic agonist.
Food interactions
None known
Human targets
7 targets
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Half-life
1.7-2.6 hours
Protein binding
56%
Metabolism
Pharmacokinetic data: DrugBank · CC BY-NC 4.0
Known interactions with other medications. Always consult a healthcare professional.
Showing 50 of 820 interactions
How the body processes this drug — absorption, distribution, metabolism, and elimination
Proteins and enzymes this drug interacts with in the body
PMID:20558321 PMID:21836131 PMID:24700710 PMID:28842488
Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages .
PMID:20558321 PMID:21836131 PMID:24700710 PMID:28842488
The inward rectification is mainly due to the blockage of outward current by internal magnesium. This channel is activated by internal ATP and can be blocked by external barium .
PMID:20558321 PMID:21836131 PMID:24700710 PMID:28842488
Can form a sulfonylurea-sensitive but ATP-insensitive potassium channel with ABCC9 (By similarity)
PMID:12808432 PMID:20562108 PMID:31155282 PMID:36502918
The current is characterized by a voltage-independent activation, an intracellular calcium concentration increase-dependent activation and a single-channel conductance of 10 picosiemens .
PMID:12808432 PMID:20562108 PMID:31155282 PMID:36502918
Also presents an inwardly rectifying current, thus reducing its already small outward conductance of potassium ions, which is particularly the case when the membrane potential displays positive values, above + 20 mV .
PMID:12808432
Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization (By similarity)
PMID:12542527 PMID:16402920
Involved in autophagy in response to starvation. Upon interaction with VMP1 and activation, controls ER-isolation membrane contacts for autophagosome formation .
PMID:28890335
Also modulates ER contacts with lipid droplets, mitochondria and endosomes .
PMID:28890335
In coordination with FLVCR2 mediates heme-stimulated switching from mitochondrial ATP synthesis to thermogenesis (By similarity)
Enzymes involved in drug metabolism — important for understanding drug interactions
ATC G02CA01
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Show
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Linked compound data from DrugBank Open Data (CC BY-NC 4.0)
Ritodrine
Additional database identifiers
Drugs Product Database (DPD)
20347
ChemSpider
599993
BindingDB
50493311
ZINC
ZINC000000057483
HUGO Gene Nomenclature Committee (HGNC)
HGNC:286
GenAtlas
ADRB2
GeneCards
ADRB2
GenBank Gene Database
Y00106
GenBank Protein Database
29371
Guide to Pharmacology
29
UniProt Accession
ADRB2_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:285
GenAtlas
ADRB1
GeneCards
ADRB1
GenBank Gene Database
J03019
GenBank Protein Database
178200
Guide to Pharmacology
28
UniProt Accession
ADRB1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:286
GenAtlas
ADRB2
GeneCards
ADRB2
GenBank Gene Database
Y00106
GenBank Protein Database
29371
Guide to Pharmacology
29
UniProt Accession
ADRB2_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:288
GenAtlas
ADRB3
GeneCards
ADRB3
GenBank Gene Database
M29932
GenBank Protein Database
178896
Guide to Pharmacology
30
UniProt Accession
ADRB3_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6255
GenAtlas
KCNJ1
GeneCards
KCNJ1
GenBank Gene Database
U12541
GenBank Protein Database
529313
Guide to Pharmacology
429
UniProt Accession
KCNJ1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6256
GeneCards
KCNJ10
Guide to Pharmacology
438
UniProt Accession
KCJ10_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6257
GenAtlas
KCNJ11
GeneCards
KCNJ11
GenBank Gene Database
D50582
GenBank Protein Database
1088445
UniProt Accession
KCJ11_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6258
GenAtlas
KCNJ12
GeneCards
KCNJ12
GenBank Gene Database
L36069
GenBank Protein Database
567019
Guide to Pharmacology
431
UniProt Accession
KCJ12_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6260
GeneCards
KCNJ14
Guide to Pharmacology
433
UniProt Accession
KCJ14_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6261
GeneCards
KCNJ15
UniProt Accession
KCJ15_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6269
GenAtlas
KCNJ8
GeneCards
KCNJ8
GenBank Gene Database
D50312
UniProt Accession
KCNJ8_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6284
GenAtlas
KCNMA1
GeneCards
KCNMA1
GenBank Gene Database
U13913
GenBank Protein Database
537439
Guide to Pharmacology
380
UniProt Accession
KCMA1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6285
GeneCards
KCNMB1
GenBank Gene Database
U25138
GenBank Protein Database
1326067
UniProt Accession
KCMB1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6286
GenAtlas
KCNMB2
GeneCards
KCNMB2
GenBank Gene Database
AF099137
UniProt Accession
KCMB2_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6287
GeneCards
KCNMB3
GenBank Gene Database
AF139471
GenBank Protein Database
5880671
UniProt Accession
KCMB3_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6289
GeneCards
KCNMB4
GenBank Gene Database
AF160967
GenBank Protein Database
7799988
UniProt Accession
KCMB4_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6293
GenAtlas
KCNN4
GeneCards
KCNN4
GenBank Gene Database
AF000972
GenBank Protein Database
2584866
Guide to Pharmacology
384
UniProt Accession
KCNN4_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6290
GeneCards
KCNN1
GenBank Gene Database
U69883
GenBank Protein Database
1575661
Guide to Pharmacology
381
UniProt Accession
KCNN1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6291
GeneCards
KCNN2
GenBank Gene Database
AF239613
GenBank Protein Database
10334701
Guide to Pharmacology
382
UniProt Accession
KCNN2_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:6292
GeneCards
KCNN3
GenBank Gene Database
AF031815
GenBank Protein Database
3309531
Guide to Pharmacology
383
UniProt Accession
KCNN3_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:13211
GenAtlas
ATP2C1
GeneCards
ATP2C1
GenBank Gene Database
AF181120
GenBank Protein Database
6715131
UniProt Accession
AT2C1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:29103
GeneCards
ATP2C2
UniProt Accession
AT2C2_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:814
GeneCards
ATP2B1
UniProt Accession
AT2B1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:815
GeneCards
ATP2B2
UniProt Accession
AT2B2_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:816
GeneCards
ATP2B3
UniProt Accession
AT2B3_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:817
GeneCards
ATP2B4
UniProt Accession
AT2B4_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:811
GeneCards
ATP2A1
GenBank Gene Database
AK291314
GenBank Protein Database
158256064
Guide to Pharmacology
840
UniProt Accession
AT2A1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:812
GeneCards
ATP2A2
GenBank Gene Database
M23114
GenBank Protein Database
306850
UniProt Accession
AT2A2_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:7590
GeneCards
MYLK
Guide to Pharmacology
1552
UniProt Accession
MYLK_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:11457
GeneCards
SULT1C4
UniProt Accession
ST1C4_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:8891
GeneCards
PGD
GenBank Gene Database
U30255
GenBank Protein Database
984325
UniProt Accession
6PGD_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:11453
GenAtlas
SULT1A1
GeneCards
SULT1A1
GenBank Gene Database
L10819
GenBank Protein Database
179042
UniProt Accession
ST1A1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:11455
GeneCards
SULT1A3
UniProt Accession
ST1A3_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:11453
GenAtlas
SULT1A1
GeneCards
SULT1A1
GenBank Gene Database
L10819
GenBank Protein Database
179042
UniProt Accession
ST1A1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:11454
GeneCards
SULT1A2
UniProt Accession
ST1A2_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:11455
GeneCards
SULT1A3
UniProt Accession
ST1A3_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:30004
GeneCards
SULT1A4
UniProt Accession
ST1A4_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:17845
GenAtlas
SULT1B1
GeneCards
SULT1B1
GenBank Gene Database
D89479
UniProt Accession
ST1B1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:11456
GeneCards
SULT1C2
UniProt Accession
ST1C2_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:33543
GeneCards
SULT1C3
UniProt Accession
ST1C3_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:11457
GeneCards
SULT1C4
UniProt Accession
ST1C4_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:11458
GenAtlas
SULT2A1
GeneCards
SULT2A1
GenBank Gene Database
L20000
GenBank Protein Database
306702
UniProt Accession
ST2A1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:14903
GeneCards
SULT4A1
UniProt Accession
ST4A1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:33433
GeneCards
SULT6B1
UniProt Accession
ST6B1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:11457
GeneCards
SULT1C4
UniProt Accession
ST1C4_HUMAN
DrugBank citations
If you use DrugBank data in your research, please cite the following publications: