Do I need a prescription for Rifapentine 150mg tablets?

Rifapentine 150mg tablets is classified as a Valid as a prescribable product in the UK. However, always consult a pharmacist or doctor before use. (Source: NHS dm+d)

What are the brand names for Rifapentine 150mg tablets?

Rifapentine 150mg tablets is the generic name. It is available under brand names including: Priftin 150mg tablets. (Source: NHS dm+d — Actual Medicinal Products)

NOT medical advice. Always consult a healthcare professional. NOT affiliated with or endorsed by the NHS, NHSBSA, MHRA, or any government body.

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NOT medical advice. Always consult a qualified healthcare professional. NOT affiliated with, or endorsed by the NHS, NHSBSA, MHRA, or any government body.

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NOT medical advice. Always consult a qualified healthcare professional. NOT affiliated with, or endorsed by the NHS, NHSBSA, MHRA, or any government body.

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Rifapentine 150mg tablets

Prescription only

Requires a prescription from a doctor or prescriber

Tablet

150mg

Oral

Rifapentine is an antibiotic drug used in the treatment of tuberculosis.

Active ingredients:

Rifapentine

ATC classificationBrowse ATC index

International classification by the WHO, grouping medicines by the organ system they act on

ATC J04AB05

Chemical classBrowse classes

Classification based on the molecule's chemical structure and properties

Check interactions for Rifapentine

No active safety alerts

Official documents, adverse reaction reporting, and safety monitoring

Report a side effect

Submit a Yellow Card report to the MHRA

Official medicine documents

Yellow Card

Report side effects (MHRA)

Drug safety updates

MHRA alerts for Rifapentine

Source: MHRA Products DatabaseOGL 3.0

Updated 3 months ago(16 Jan 2026)

Safety monitoring data

Yellow Card reports

MHRA

The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.

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Report a side effect

Submit a Yellow Card report to the MHRA

Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.

EudraVigilance

EMA

The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.

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Browse substances A–Z in the European adverse reaction database

About EudraVigilance

Learn about EU pharmacovigilance and safety monitoring

EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.

1 branded products available

1 productsShow details

1 products

Possibly available on the UK marketRestricted supplyDiscontinuedAvailability per NHS dm+d

MHRA licensed products

View all licensed products for Rifapentine on the MHRA register

Priftin 150mg tablets

Imported (United States)

None

Imported

Source: NHS dm+dOGL 3.0

Updated about 1 month ago(1 Mar 2026)

Therapeutically similar medicines

10 similarShow details

Rifampicin 210mg/5ml oral solution

Oral solution

210mg/5ml

Same therapeutic group

Rifampicin 210mg/5ml oral suspension

Oral suspension

210mg/5ml

Same therapeutic group

Rifabutin 100mg/5ml oral solution

Oral solution

100mg/5ml

Same therapeutic group

Rifabutin 150mg/5ml oral solution

Oral solution

150mg/5ml

Same therapeutic group

Rifabutin 50mg/5ml oral solution

Oral solution

50mg/5ml

Same therapeutic group

Similarity based on WHO Anatomical Therapeutic Chemical (ATC) classification and NHS BNF section grouping. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.

Clinical guidelines and formulary information

British National Formulary

Rifapentine

BNF

Drug monograph — bnf.nice.org.uk

Source: British National Formulary, NICE. Joint Formulary Committee. Contains public sector information licensed under the Open Government Licence v3.0.

Check stock at pharmacies and supply information

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Pharmacy stock checkers

Search for this medicine at major UK pharmacy chains. These links open the retailer's own website — results depend on their current online catalogue.

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DeliveryNHS

Supply & product information

Official product databases and supply status monitoring

Shortages info

NHS Specialist Pharmacy Service (SPS)

emc product search

Discontinuations & alternatives for Rifapentine

Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. emc (electronic medicines compendium) is operated by Datapharm Ltd. Shortage information sourced from NHS Specialist Pharmacy Service (SPS), sps.nhs.uk.

Codes for healthcare professionals and prescribing systems

Show details

These codes are used by healthcare IT systems and prescribers to identify this medicine.

NHS UK identifiers

SNOMED CT

41954811000001103

dm+d ID

41954811000001103

VTM (Virtual Therapeutic Moiety)

777439001

VMP (Virtual Medicinal Product)

41954811000001103

International identifiers

ATC code — Anatomical Therapeutic Chemical (WHO)

J04AB05

Browse tools

dm+d Browser

NHSBSA medicines dictionary lookup

SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF codes from NHS Business Services Authority (NHSBSA). ATC codes from the WHO Collaborating Centre for Drug Statistics Methodology (whocc.no).

Active and completed clinical studies from ClinicalTrials.gov

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Searching UK clinical trials...

Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.

Pharmacology and chemical data from DrugBank

go.drugbank.com

Key facts

Drug status

Approved

Major interactions

None known

Half-life

Not available

Mechanism

Rifapentine has shown higher bacteriostatic and bactericidal activities especial…

Food interactions

1 warning

Human targets

None mapped

Data: DrugBank · CC BY-NC 4.0

Pharmacokinetics at a glance

Absorption

Rapidly and well absorbed from the gastrointestinal tract.

Protein binding

97.7%

97.7% (bound to plasma proteins)

Volume of distribution

9.1 L

* 70.2 ± 9.1 L

Metabolism

Hepatic

Elimination

600 mg

Following a single 600 mg oral dose of radiolabeled rifapentine to healthy volunteers (n=4), 87% of the total 14C rifapentine was recovered in the urine (17%) and feces (70%).…

Clearance

0.14 L/h

* Apparent Oral cl=2.51 +/- 0.14 L/h [Male tuberculosis patients who received 600 mg rifapentine in combination with isoniazid, pyrazinamide and ethambutol]
* Apparent Oral cl=1.69…

Pharmacokinetic data: DrugBank · CC BY-NC 4.0

Status:

Approved

Investigational

Small molecule

About this compound

Rifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.

Properties:

solid

Avg. mass: 877.03 Da

DrugBank indication

For the treatment of pulmonary tuberculosis.

Also known as(79)

3-(((4-Cyclopentyl-1-piperazinyl)imino)methyl)rifamycin

Cyclopentylrifampicin

Rifapentin

Rifapentine

2.7.7.6

RNA polymerase subunit beta'

RNAP subunit beta'

Transcriptase subunit beta'

Dosage forms(3)

Tablet, coated (Oral) — 150 mg

Tablet, film coated (Oral) — 150 mg/1

Tablet, film coated (Oral) — 150 mg

Molecular properties(19)

Drug interactions(972)

Known interactions with other medications. Always consult a healthcare professional.

Aripiprazole

Moderate

DB01238

The metabolism of Aripiprazole can be increased when combined with Rifapentine.

Rifapentine 150mg tablets

Safety & regulatory

Official medicine documents

Safety monitoring data

Yellow Card reports

EudraVigilance

Brand versions and licensed products

Medicines like this

Guidance (NICE / BNF)

British National Formulary

Availability, stocks & shortages

Pharmacy stock checkers

Supply & product information

Professional identifiers

NHS UK identifiers

International identifiers

Browse tools

Clinical trials

DrugBank data

Key facts

Pharmacokinetics at a glance

Absorption

Protein binding

Volume of distribution

Metabolism

Elimination

Clearance

Clinical essentials

Pharmacology

Deep science6

Chemical identifiers

Rifapentine

Additional database identifiers

International reference pricing

DrugBank citations

Rifapentine 150mg tablets

Safety & regulatory

Official medicine documents

Safety monitoring data

Yellow Card reports

EudraVigilance

Brand versions and licensed products

Medicines like this

Guidance (NICE / BNF)

British National Formulary

Availability, stocks & shortages

Pharmacy stock checkers

Supply & product information

Professional identifiers

NHS UK identifiers

International identifiers

Browse tools

Clinical trials

DrugBank data

Key facts

Pharmacokinetics at a glance

Absorption

Protein binding

Volume of distribution

Metabolism

Elimination

Clearance

Clinical essentials

Pharmacology

Deep science6

Chemical identifiers

Rifapentine

Additional database identifiers

International reference pricing

DrugBank citations

Deep science
6

Deep science
6