Passiflora incarnata 30c homeopathic tablets

Background: Stress is a natural response of the body, induced by factors of a physical (hunger, thirst, and infection) and/or psychological (perceived threat, anxiety, or concern) nature. Chronic, long-term stress may cause problems with sleep, concentration, and memory, as well as affective disorders. The passionflower (Passiflora incarnata) is a perennial plant with documented therapeutic properties. The literature data suggest that the passionflower itself, as well as its preparations, helps reduce stress and can therefore be helpful in the treatment of insomnia, anxiety, and depression. The objective of this systematic review was to evaluate Passiflora incarnata in terms of its neuropsychiatric effects. Methods: The scientific databases PubMed, ClinTrials.gov, and Embase were searched up to 22 October 2019. The search identified randomized clinical trials describing the effects of Passiflora incarnata in neuropsychiatric disorders. Results: The systematic review included nine clinical trials. The duration of the studies included in the analysis varied widely, from one day up to 30 days. Study participants were no less than 18 years old. In each of the papers, the effects of passionflower were measured by using a number of different tests and scales. The majority of studies reported reduced anxiety levels following the administration of Passiflora incarnata preparations, with the effect less evident in people with mild anxiety symptoms. No adverse effects, including memory loss or collapse of psychometric functions, were observed. Conclusion: Passiflora incarnata may be helpful in treating some symptoms in neuropsychiatric patients.

Abstract licence: CC BY 4.0

Passiflora incarnata L., commonly known as passionflower, is traditionally cultivated as an ornamental plant but has demonstrated diverse therapeutic potential. Its pharmacological effects are attributed to bioactive compounds such as flavonoids and alkaloids, which influence multiple biological pathways. This review aims to summarise and critically analyse recent findings on the pharmacological properties of Passiflora incarnata L., focusing on its neuropsychiatric, antioxidant, antimicrobial, and anticancer activities. A targeted literature search was conducted in PubMed, Scopus, Web of Science, and Google Scholar for peer-reviewed publications between 2000 to 2025. Relevant articles were screened, and a more appropriate article related to the objective of the review was selected. Some classical papers are also cited as per the requirement of the topic. Passiflora incarnata L. showed multifunctional medicinal properties with various applications in neuropsychiatry, oxidative stress management, antimicrobial agent, and as an anticancer agent. The U.S. Food and Drug Administration categorizes passionflower extracts as “generally recognized as safe”. However, most evidence remains preclinical, with methodological variation limiting generalisation. Standardised formulation, robust clinical trials, and in-depth in vivo studies are essential to establish its therapeutic relevance and safety in modern medicine.

Abstract licence: CC BY

Passiflora incarnata Linn, commonly referred to as passionflower, is a traditional medicinal herb renowned for its soothing effects on the nervous system. It has long been utilized in the treatment of sleep disturbances, anxiety-related conditions, and inflammatory disorders. In recent years, growing scientific interest has positioned P. incarnata as a promising phytotherapeutic agent, particularly for neuropsychiatric and neuroprotective applications. The present review provides a comprehensive and integrative overview of P. incarnata, emphasizing its botanical characteristics, phytochemical composition, extraction methodologies, and pharmacological activities. Special attention is given to both conventional and advanced extraction techniques, highlighting how process parameters influence the recovery of flavonoids, alkaloids, and phenolic compounds responsible for the plant’s biological activity. The review summarizes current evidence supporting the sedative, anxiolytic, anticonvulsant, antidepressant, antioxidant, anti-inflammatory, antidiabetic, antimicrobial, and anticancer properties of P. incarnata. Mechanistic insights, particularly those involving modulation of the GABAergic system and oxidative stress pathways, are discussed to explain its neuropharmacological effects. Furthermore, the sustainable utilization of Passiflora biomass and the need for standardized extracts, optimized extraction protocols, and well-designed clinical studies are critically addressed. Overall, this review highlights P. incarnata as a valuable natural resource with significant therapeutic potential and underscores future research directions required for its successful translation into evidence-based herbal formulations. This review critically evaluates existing literature, provides comparative analysis of extraction techniques, and highlights key research gaps for future investigations.

Abstract licence: CC BY-NC