Methoxsalen 1.2% bath additive
Requires a prescription from a doctor or prescriber
A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia.
Official documents, adverse reaction reporting, and safety monitoring
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Official medicine documents
Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
View Drug Analysis Profile
Suspected adverse reactions reported for Methoxsalen
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Interactive Drug Analysis Profiles for all medicines
Report a side effect
Submit a Yellow Card report to the MHRA
Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.
View EudraVigilance report
Suspected adverse reactions reported for Methoxsalen
About EudraVigilance
Learn about EU pharmacovigilance and safety monitoring
EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
1 branded products available
Therapeutically similar medicines
Other
(3)Similarity is based on WHO Anatomical Therapeutic Chemical (ATC) classification and on a factual NHS dm+d therapeutic-grouping code prefix. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.
Check stock at pharmacies and supply information
Pharmacy stock checkers
Search for this medicine at major UK pharmacy chains. These links open the retailer's own website — results depend on their current online catalogue.
Supply & safety information
Official UK regulator monitoring and safety alerts
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. Shortage and safety information sourced from MHRA drug safety updates (gov.uk, Crown Copyright under OGL v3.0).
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
Browse tools
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF code shown is the factual mapping value distributed by NHS Business Services Authority (NHSBSA) in the dm+d supplementary file under OGL v3.0; it is not affiliated with, nor licensed from, the publishers of the British National Formulary. ATC codes from the WHO Collaborating Centre for Drug Statistics Methodology (whocc.no).
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing the 50 most relevant studies.
Reviews & meta-analyses: 4 · Trials: 3 · 1959–2026
Showing the 50 most relevant studies, sorted by most relevant.
R. Stern, Elissa J. Lunder
Archives of dermatology, 1998
- Carcinoma, Squamous Cell
- Psoriasis
- PUVA Therapy
John A. Parrish, Thomas B. Fitzpatrick, Lewis Tanenbaum, et al.
New England Journal of Medicine, 1974
- Cell Division
- Depression, Chemical
- DNA
Robert S. Stern, Khanh T. Nichols, Liisa Väkevä
New England Journal of Medicine, 1997
- Melanoma
- Methoxsalen
- Psoriasis
Robert S. Stern, L. A. Thibodeau, Ruth A. Kleinerman, et al.
New England Journal of Medicine, 1979
- Basal Cell Carcinoma
- Carcinoma, Basal Cell
- Carcinoma, Squamous Cell
John W. Melski, Lewis Tanenbaum, John A. Parrish, et al.
Journal of Investigative Dermatology, 1977
- Erythema
- Methoxsalen
- Nausea
Barbara A. Gilchrest, John A. Parrish, Lewis Tanenbaum, et al.
Cancer, 1976
- Mechlorethamine
- Methoxsalen
- Mycosis Fungoides
Jason K. Yano, Mei‐Hui Hsu, Keith J. Griffin, et al.
Nature Structural & Molecular Biology, 2005
- Aryl Hydrocarbon Hydroxylases
- Coumarins
- Mixed Function Oxygenases
B. Baroli, B. Baroli, M. López-Quintela, et al.
Journal of controlled release : official journal of the Controlled Release Society, 2000
- Administration, Topical
- Chemistry, Physical
- Chromatography, High Pressure Liquid
Klaus Wolff
Archives of Dermatology, 1976
- Dose-Response Relationship, Radiation
- Long-Term Care
- Methoxsalen
Elissa J. Lunder, Robert S. Stern
New England Journal of Medicine, 1998
- Carcinoma, Merkel Cell
- Methoxsalen
- PUVA Therapy
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
None known
Half-life
2 hours
Mechanism
After activation it binds preferentially to the guanine and cytosine moieties of…
Food interactions
1 warning
Human targets
2 targets
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Half-life
2 hours
Elimination
95%
Pharmacokinetic data: DrugBank · CC BY-NC 4.0
Known interactions with other medications. Always consult a healthcare professional.
Showing 50 of 878 interactions
How the body processes this drug — absorption, distribution, metabolism, and elimination
Proteins and enzymes this drug interacts with in the body
Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity
Enzymes involved in drug metabolism — important for understanding drug interactions
ATC D05BA02
ATC D05AD02
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
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Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Linked compound data from DrugBank Open Data (CC BY-NC 4.0)
Methoxsalen
Additional database identifiers
Drugs Product Database (DPD)
5303
ChemSpider
3971
BindingDB
50041234
PDB
8MO
ZINC
ZINC000002548959
HUGO Gene Nomenclature Committee (HGNC)
HGNC:2610
GenAtlas
CYP2A6
GeneCards
CYP2A6
GenBank Gene Database
X13897
Guide to Pharmacology
1321
UniProt Accession
CP2A6_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:2595
GeneCards
CYP1A1
GenBank Gene Database
K03191
GenBank Protein Database
181276
Guide to Pharmacology
1318
UniProt Accession
CP1A1_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:2608
GeneCards
CYP2A13
GenBank Gene Database
AF209774
GenBank Protein Database
11494143
Guide to Pharmacology
1323
UniProt Accession
CP2AD_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:2610
GenAtlas
CYP2A6
GeneCards
CYP2A6
GenBank Gene Database
X13897
Guide to Pharmacology
1321
UniProt Accession
CP2A6_HUMAN
HUGO Gene Nomenclature Committee (HGNC)
HGNC:2596
GenAtlas
CYP1A2
GeneCards
CYP1A2
GenBank Gene Database
Z00036
Guide to Pharmacology
1319
UniProt Accession
CP1A2_HUMAN
DrugBank citations
If you use DrugBank data in your research, please cite the following publications:
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Structured knowledge from the free knowledge base
Linked open data from Wikidata (Q408570), a free and open knowledge base operated by the Wikimedia Foundation. Data is available under the Creative Commons CC0 1.0 Public Domain Dedication.