Magnesium oxide 375mg capsules
Requires a prescription from a doctor or prescriber
Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase.
Official documents, adverse reaction reporting, and safety monitoring
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Official medicine documents
Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
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Suspected adverse reactions reported for Magnesium oxide
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Report a side effect
Submit a Yellow Card report to the MHRA
Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.
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Suspected adverse reactions reported for Magnesium oxide
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EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
1 branded products available
Part of the AdMag brand family (generic: Magnesium oxide)
MHRA licensed products
View all licensed products for Magnesium oxide on the MHRA register
Therapeutically similar medicines
Similarity is based on WHO Anatomical Therapeutic Chemical (ATC) classification and on a factual NHS dm+d therapeutic-grouping code prefix. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.
NHS prescribing volume and spending trends
Guidelines from the National Institute for Health and Care Excellence
NICE clinical guidance(2)
Preventing recurrent hypomagnesaemia: oral magnesium glycerophosphate (ESUOM4)
Hypertension in pregnancy: diagnosis and management (NG133)
Source: National Institute for Health and Care Excellence (NICE). Contains public sector information licensed under the Open Government Licence v3.0.
Check stock at pharmacies and supply information
Pharmacy stock checkers
Search for this medicine at major UK pharmacy chains. These links open the retailer's own website — results depend on their current online catalogue.
Supply & safety information
Official UK regulator monitoring and safety alerts
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. Shortage and safety information sourced from MHRA drug safety updates (gov.uk, Crown Copyright under OGL v3.0).
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
Browse tools
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF code shown is the factual mapping value distributed by NHS Business Services Authority (NHSBSA) in the dm+d supplementary file under OGL v3.0; it is not affiliated with, nor licensed from, the publishers of the British National Formulary. ATC codes from the WHO Collaborating Centre for Drug Statistics Methodology (whocc.no).
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing the 50 most relevant studies.
Reviews & meta-analyses: 11 · Randomised trials: 5 · 1984–2026
Showing the 50 most relevant studies, sorted by most relevant.
N. Ahmed, Baige Zhang, Bilquees Bozdar, et al.
Frontiers in Plant Science, 2023
Fong Wang, Stephen K. Van Den Eeden, Lynn Ackerson, et al.
Headache The Journal of Head and Face Pain, 2003
- Magnesium Oxide
- Migraine Disorders
- Recurrence
Yusuke Sakaguchi, Takayuki Hamano, Yoshitsugu Obi, et al.
Journal of the American Society of Nephrology, 2019
- Carbon
- Coronary Artery Disease
- Hospitals, University
S. Abinaya, Helen P. Kavitha, Muthuramalingam Prakash, et al.
Sustainable Chemistry and Pharmacy, 2021
Malaiappan S, Harris J
2024
Zhao-Qi Zhang, Yong-Xin Yang, Jing-an Li, et al.
Bioactive Materials, 2021
Robert Kennedy Otieno, Edward V. Odhong, Alex Munyasia Muumbo
Next Materials, 2026
2025
H. C. S. Perera, Vijayakumar Gurunanthanan, Anoop Singh, et al.
Journal of Magnesium and Alloys, 2024
Jawad Ali, Kun Zhan, Haibin Wang, et al.
Environmental Science & Technology, 2020
- Magnesium Oxide
- Peroxides
- Electron Transport
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
69 found
Half-life
Not available
Mechanism
The term "Milk of Magnesia" was first used to describe a white aqueous, mildly a…
Food interactions
2 warnings
Human targets
None mapped
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Magnesium oxide, in combination with sodium picosulfate and anhydrous citric acid, is indicated for cleansing of the colon as a preparation for colonoscopy in adults and pediatric patients ages 9 years and older.
[L43832]
Known interactions with other medications. Always consult a healthcare professional.
Showing 50 of 743 interactions
ATC A02AA02
ATC A12CC10
ATC A06AD02
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
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Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Linked compound data from DrugBank Open Data (CC BY-NC 4.0)
Magnesium oxide
DrugBank citations
If you use DrugBank data in your research, please cite the following publications:
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Structured knowledge from the free knowledge base
Molecular structure

Linked open data from Wikidata (Q214769), a free and open knowledge base operated by the Wikimedia Foundation. Data is available under the Creative Commons CC0 1.0 Public Domain Dedication. Molecular structure images from Wikimedia Commons.