Iodine aqueous topical solution
Requires a prescription from a doctor or prescriber
Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperthyroidism (also known as thyroid storm or thyrotoxic crisis).
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Yellow Card reports
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Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
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EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
1 branded products available
Therapeutically similar medicines
Similarity is based on WHO Anatomical Therapeutic Chemical (ATC) classification and on a factual NHS dm+d therapeutic-grouping code prefix. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.
Guidelines from the National Institute for Health and Care Excellence
NICE clinical guidance(1)
Source: National Institute for Health and Care Excellence (NICE). Contains public sector information licensed under the Open Government Licence v3.0.
Check stock at pharmacies and supply information
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Supply & safety information
Official UK regulator monitoring and safety alerts
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. Shortage and safety information sourced from MHRA drug safety updates (gov.uk, Crown Copyright under OGL v3.0).
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
Browse tools
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF code shown is the factual mapping value distributed by NHS Business Services Authority (NHSBSA) in the dm+d supplementary file under OGL v3.0; it is not affiliated with, nor licensed from, the publishers of the British National Formulary. ATC codes from the WHO Collaborating Centre for Drug Statistics Methodology (whocc.no).
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing the 50 most relevant studies.
Reviews & meta-analyses: 9 · Randomised trials: 4 · 1947–2026
Showing the 50 most relevant studies, sorted by most relevant.
Daniel Glinoer, P. De Nayer, François Delange, et al.
The Journal of Clinical Endocrinology & Metabolism, 1995
- Iodine
- Potassium Iodide
- Pregnancy Complications
Joffrey Huve, Andrey Ryzhikov, Habiba Nouali, et al.
RSC Advances, 2018
Adrienne Hatch‐McChesney, Harris R. Lieberman
Nutrients, 2022
- Iodine
- Malnutrition
- Iodides
Inger Aakre, Inger Beate Tveit, L. Myrmel, et al.
Food Science & Nutrition, 2023
Sarkees M, Alafif H, Alsalameh SA, et al.
2025
- Periapical Periodontitis
- Iodine Compounds
- Potassium Iodide
ObjectiveThis study aimed to evaluate the antibacterial effectiveness of two concentrations of iodine-potassium iodide (IKI) used as the final irrigating solution during endodontic retreatment.MethodsThirty symptom-free root-filled anterior teeth with chronic apical periodontitis (ResultsIrrigation with 5% IKI resulted in significantly reduced bacterial counts than 2% IKI irrigation (pConclusionThe use of a 5% IKI solution as the final irrigating agent in endodontic retreatment cases with chronic apical periodontitis significantly reduces bacterial counts compared to a 2% IKI solution. The 5% IKI solution therefore exhibited a superior antibacterial effect. Consequently, 5% IKI solution application improves microbiological outcomes and enhances the overall disinfection of the root canal system. (EEJ-2024-08-131).
Abstract licence: CC BY-NC 4.0
Traksel R, Broen J, van Henten A, et al.
2026
- Lung
- Iodine
- Interferon Type I
Michael Zimmermann, Maria Andersson
Nutrition Reviews, 2012
- Nutritional Status
- Nutrition Assessment
- Goiter
Sarah Barker, Michael Humphrey, Mayo H. Soley
Journal of Clinical Investigation, 1951
- Blood
- Iodine
- Iodine Isotopes
A. S. McFarlane
Biochemical Journal, 1956
- Blood Proteins
- Iodine
- Iodine Radioisotopes
Ronald O. Rahn
Photochemistry and Photobiology, 1997
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
None known
Half-life
Not available
Mechanism
Not available
Food interactions
None known
Human targets
1 target
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Known interactions with other medications. Always consult a healthcare professional.
Showing 50 of 621 interactions
ATC S01XA04
ATC V03AB21
ATC R05CA02
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
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Chemical identifiers
CAS, UNII, InChI Key and database cross-references
DrugBank citations
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Structured knowledge from the free knowledge base
Wikipedia article
used as an antiseptic and a means of treating and preventing iodine deficiency
Read on WikipediaMolecular structure
ATC classifications (Wikidata)
Linked open data from Wikidata (Q28196266), a free and open knowledge base operated by the Wikimedia Foundation. Data is available under the Creative Commons CC0 1.0 Public Domain Dedication. Molecular structure images from Wikimedia Commons.