House dust mites (Dermatophagoides pteronyssinus and Dermatophagoides farinae) allergen extract 12 SQ-HDM oral lyophilisates sugar free
Requires a prescription from a doctor or prescriber
House dust allergenic extract is used in allergenic testing.
Official documents, adverse reaction reporting, and safety monitoring
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Official medicine documents
Yellow Card
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Drug safety updates
MHRA alerts for House dust mite
Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
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Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.
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EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
2 branded products available
MHRA licensed products
View all licensed products for House dust mite on the MHRA register
Acarizax 12 SQ-HDM oral lyophilisates
Therapeutically similar medicines
Similarity is based on WHO Anatomical Therapeutic Chemical (ATC) classification and on a factual NHS dm+d therapeutic-grouping code prefix. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.
NHS prescribing volume and spending trends
Guidelines from the National Institute for Health and Care Excellence
NICE clinical guidance(6)
12 SQ-HDM SLIT for treating allergic rhinitis and allergic asthma caused by house dust mites (TA1045)
Indoor air quality at home (NG149)
Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN) (NG245)
Intranasal phototherapy for allergic rhinitis (HTG473)
Atopic eczema in under 12s (QS44)
ImmunoCAP ISAC 112 for multiplex allergen testing (HTG413)
Source: National Institute for Health and Care Excellence (NICE). Contains public sector information licensed under the Open Government Licence v3.0.
Check stock at pharmacies and supply information
Pharmacy stock checkers
Search for this medicine at major UK pharmacy chains. These links open the retailer's own website — results depend on their current online catalogue.
Supply & safety information
Official UK regulator monitoring and safety alerts
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. Shortage and safety information sourced from MHRA drug safety updates (gov.uk, Crown Copyright under OGL v3.0).
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
Browse tools
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. ATC codes from the WHO Collaborating Centre for Drug Statistics Methodology (whocc.no).
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing the 50 most relevant studies.
Reviews & meta-analyses: 12 · Randomised trials: 11 · 1967–2026
Showing the 50 most relevant studies, sorted by most relevant.
P. C Gotzsche, C. Hammarquist, Michael Burr
BMJ, 1998
- Allergens
- Asthma
- Dust
Peter C Gøtzsche, Helle Krogh Johansen
Allergy, 2008
- Pyroglyphidae
- Allergens
- Asthma
Holger Mosbech, Regina Deckelmann, F. de Blay, et al.
Journal of Allergy and Clinical Immunology, 2014
- Administration, Inhalation
- Administration, Sublingual
- Adrenal Cortex Hormones
Aarif O. Eifan, Tunç Akkoç, Aysel Yıldız, et al.
Clinical & Experimental Allergy, 2010
- Immunotherapy
- Administration, Sublingual
- Asthma
Enrico Compalati, Giovanni Passalacqua, Matteo Bonini, et al.
Allergy, 2009
- Administration, Sublingual
- Allergens
- Asthma
M. Walshaw, C. Evans
The Quarterly journal of medicine, 1986
- Asthma
- Bedding and Linens
- Beds
H. Nolte, D. Bernstein, H. Nelson, et al.
The Journal of allergy and clinical immunology, 2016
Pernille Vigand Hegner, MSt, Anne Sofie Rysgaard, MSt, Alma Holm Rovsing, MD, PhD, et al.
Current Therapeutic Research, 2025
Alqutub A, Abumohssin AG, Alqutub ST, et al.
2026
L. Gregory, C. Lloyd
Trends in immunology, 2011
- Adrenal Cortex Hormones
- Allergens
- Asthma
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
None known
Half-life
Not available
Mechanism
Not available
Food interactions
None known
Human targets
None mapped
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
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Chemical identifiers
CAS, UNII, InChI Key and database cross-references
DrugBank citations
If you use DrugBank data in your research, please cite:
- DrugBank 6.02024Recommended citationKnox C., Wilson M., Klinger C.M., et alDrugBank 6.0: the DrugBank Knowledgebase for 2024Nucleic Acids Res. 2024 Jan 552(D1):D1265-D1275
- DrugBank 5.02018Wishart D.S., Feunang Y.D., Guo A.C., et alDrugBank 5.0: a major update to the DrugBank database for 2018Nucleic Acids Res. 2017 Nov 846(D1):D1074-D1082
- DrugBank 4.02014Law V., Knox C., Djoumbou Y., et alDrugBank 4.0: shedding new light on drug metabolismNucleic Acids Res. 2014 Jan 142(1):D1091-7
- DrugBank 3.02011Knox C., Law V., Jewison T., et alDrugBank 3.0: a comprehensive resource for 'omics' research on drugsNucleic Acids Res. 2011 Jan39(Database issue):D1035-41
- DrugBank 2.02008Wishart D.S., Knox C., Guo A.C., et alDrugBank: a knowledgebase for drugs, drug actions and drug targets.Nucleic Acids Research2008 Jan36(Database issue):D901-6
- DrugBank 1.02006Wishart D.S., Knox C., Guo A.C., et alDrugBank: a comprehensive resource for in silico drug discovery and exploration.Nucleic Acids Research2006 Jan 134(Database issue):D668-72