Chromium 500microgram capsules

Metabolic syndrome (MetS) is a complex interplay of interrelated metabolic derangements, including insulin resistance, dyslipidemia, central adiposity, and hypertension, thereby markedly amplifying the predisposition to type 2 diabetes mellitus (T2DM) and cardiovascular morbidities. Chromium (Cr), an indispensable trace element, has garnered scientific interest for its putative role in augmenting insulin sensitivity and modulating glucose metabolism. Chromium deficiency has been linked with insulin resistance and diabetes mellitus. A cycle of low chromium, defective glucose metabolism, and further loss of chromium is documented. Chromium supplementation has been associated with encouraging improvements in insulin sensitivity. It may enhance insulin signaling, regulate lipid metabolism, and mitigate obesity-related dysfunctions. However, its therapeutic efficacy remains debated due to inconsistent clinical outcomes and study variations. This comprehensive review delves into the implications of chromium supplementation, particularly chromodulin, in the context of MetS and its associated pathological sequelae. In conclusion, chromium (Cr) enhances insulin sensitivity by directly activating the insulin receptor kinase, which lowers the required insulin concentration for maximal cellular response and improves glucose uptake and storage. Synthesis of the evidence shows that Chromium (Cr) supplementation significantly benefits individuals with chromium deficiency or diabetes, improving glucose homeostasis and insulin sensitivity. This highlights the importance of baseline metabolic status in the effectiveness of Cr as a treatment, indicating that targeted interventions may be needed for optimal results in those with metabolic disturbances.

Abstract licence: CC BY-NC

Purpose: This study aimed to assess the effectiveness of ultrasonic denture hygiene interventions in improving denture cleanliness among elderly individuals. Materials and methods: Sixty-six participants who had received upper metal framework removable partial dentures within the past 5 years were randomly allocated into three denture hygiene intervention groups: group 1 (mechanical cleaning with a toothbrush and ultrasonic cleaning with cetylpyridinium chloride), group 2 (mechanical cleaning with a toothbrush and ultrasonic cleaning with distilled water), and control (mechanical cleaning with a toothbrush only). Denture cleanliness was assessed at baseline and 1-month using: i) Denture Cleanliness Index (DCI) scores; ii) plaque coverage percentage; and (iii) microbiological samples for bacterial and yeast detection. Differences between groups were assessed with one-way analysis of variance and Chi-squared tests. Results: Mean DCI scores and mean percentages of plaque coverage area were significantly reduced in group 1 and group 2, compared to the control group for both cobalt chromium (CoCr) and acrylic fitting surfaces (p<0.001). No significant differences were found between groups 1 and 2 with regard to the prevalence and viable counts of yeasts or total microbial viable counts. No significant differences in the investigated clinical and microbiological parameters were observed between CoCr and acrylic surfaces following the intervention period. Conclusion: The ultrasonic cleaner was significantly more effective than mechanical cleaning in the reduction of biofilm coverage on metal framework removable partial dentures over a 1-month intervention period. Nevertheless, the adjunctive use of cetylpyridinium chloride with ultrasonic cleaning did not yield additional benefits.

Abstract licence: CC BY-NC-ND

As a type of metallurgical solid waste with a significant output, chromium-containing metallurgical dust and slag are gaining increasing attention. They mainly include stainless steel dust, stainless steel slag, ferrochrome dust, and ferrochrome slag, which contain significant amounts of valuable elements, such as chromium, iron, and zinc, as well as large amounts of toxic substances, such as hexavalent chromium. Achieving the harmless and resourceful comprehensive utilization of chromium-containing metallurgical dust and slag is of great significance to ensuring environmental safety and the sustainable development of resources. This paper outlines the physicochemical properties of stainless steel dust, stainless steel slag, ferrochrome dust, and ferrochrome slag. The current treatment technologies of chromium-containing metallurgical dust and slag by hydrometallurgy, the pyrometallurgical process, and the stabilization/solidification process are introduced. Moreover, the comprehensive utilization of resources of chromium-containing metallurgical dust and slag in the preparation processes of construction materials, glass ceramics, and refractories is elaborated. The aim of this paper is to provide guidance for exploring effective technology to solve the problem of chromium-containing metallurgical dust and slag.

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Chromium slag, a chromium-bearing solid waste characterized by substantial environmental hazards yet with appreciable resource potential, has become a focal topic in solid-waste pollution control and the circular economy. Centered on the overarching logic of "evidence chain-system boundary-scalable and verifiable acceptance," this review systematically synthesizes recovery technologies, industrial-scale utilization pathways, and the key challenges associated with the detoxification and resource utilization of chromium slag. From the perspective of recovery technologies, we examine pyrometallurgical and hydrometallurgical routes, solidification/stabilization (S/S), and bioelectrochemical coupling approaches, elucidating their fundamental principles, applicability boundaries, and critical nodes where environmental burdens may be transferred across media. We emphasize that process design should concurrently consider detoxification efficiency, resource recovery performance, and whole-process pollution control. Regarding utilization pathways, this review highlights three major routes with strong scale-up relevance-metallurgical process co-treatment (CAP-sintering-blast furnace), bulk utilization in construction materials, and high-value utilization-and analyzes their industrial potential and engineering constraints. Particular attention is given to the lack of long-term leaching and durability evidence, which represents a central bottleneck limiting product-side credibility. Furthermore, we discuss cross-cutting challenges including the long-term stabilization of Cr(VI), the verifiability of "green utilization" concepts, cost and economic feasibility, and standardized acceptance criteria. We propose that future research should shift from single-process optimization toward multi-objective, system-level evaluation, and establish a full-chain evidence system covering "speciation/mineral phases-process mechanisms-environmental behavior-risk assessment-engineering scale-up-standardized acceptance." This review aims to provide a systematic analytical framework and practical reference for improving comparability across resource-utilization technologies and supporting engineering decision-making for chromium slag management.

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This article reports the results of a study of Cr(VI) ions mutagenicity in the erythrocytes of Bufo viridis tadpoles under the influence of a low-frequency pulsed magnetic field (LF PMF). The tadpoles were randomly divided into 14 groups ( n = 7). One group of intact tadpoles served as control. Other groups were experimental. The first six groups were placed for 24 h in water containing Cr(VI) at different concentrations (0.025, 0.05, 0.125, 0.25, 0.375, and 0.50 mg/L). The eighth group was subjected to an 8-h exposure to LF PMF (41 mT, 16 Hz). The remaining six groups of tadpoles were kept for 24 h in water with Cr(VI) ions at the specified concentrations and were also irradiated with LF PMF (41 mT, 16 Hz) during the first 8 h of this period. A day after the exposure, blood smears were taken, and the frequencies of micronuclei and nuclear anomalies in erythrocytes were analyzed. The results reveal that low concentrations of Cr(VI) (0.025 and 0.05 mg/L), unlike the higher ones (0.125 mg/L and above), did not significantly affect the frequencies of the analyzed anomalies. The combined action of Cr(VI) and LF PMF significantly increased the frequencies of the recorded anomalies in all the six variants of the experiment. The synergistic effect of Cr(VI) and LF PTF was shown.

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This study investigates the mechanical, tribological, and electrochemical behaviour of a novel precipitation-hardenable martensitic alloy produced by selective laser melting (SLM). The alloy was specifically engineered with an optimised composition, free from cobalt and molybdenum, and featuring reduced nickel content (7 wt.%) and 8 wt.% chromium. It has been developed as a cost-effective and sustainable alternative to conventional maraging steels, while maintaining high mechanical strength and a refined microstructure tailored to the steep thermal gradients inherent to the SLM process. Several ageing heat treatments were assessed to evaluate their influence on microstructure, hardness, tensile strength, retained austenite content, dislocation density, as well as wear behaviour (pin-on-disc test) and corrosion resistance (polarisation curves in 3.5%NaCl). The results indicate that ageing at 540 °C for 2 h offers an optimal combination of hardness (550–560 HV), tensile strength (~1700 MPa), microstructural stability, and wear resistance, with a 90% improvement compared to the as-built condition. In contrast, ageing at 600 °C for 1 h enhances ductility and corrosion resistance (Rp = 462.2 kΩ; Ecorr = –111.8 mV), at the expense of a higher fraction of reverted austenite (~34%) and reduced hardness (450 HV). This study demonstrates that the mechanical, surface, and electrochemical performance of this novel SLM-produced alloy can be effectively tailored through controlled thermal treatments, offering promising opportunities for demanding applications requiring a customised balance of strength, durability, and corrosion behaviour.

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The laser welded joint of 2000MPa cold rolled annealed hot pressed steel (PHS) is easy to break during cold rolling. In this paper, the laser welding method is used to butt weld four kinds of PHS2000 with a thickness of 3.5mm. The four kinds of PHS2000 steel are added with elements of 0% Nb, 0.04% Nb, 0.06% Nb + Cr and 0.08% Nb + Cr. The microstructure of the four kinds of welded joints is compared and analyzed. The mechanical properties of the four kinds of joints are compared through hardness test and tensile test. The results show that after adding 0.04% Nb, residual austenite appears in the weld zone and fully quenched zone, the width of columnar crystal decreases, the average hardness of the weld zone decreases from 595HV to 408HV, and the tensile strength increases from 608MPa to more than 800MPa. For chromium containing steel, the increase of niobium content can reduce the size of columnar crystal in weld zone.

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Abstract New limited pyrochlore solid solutions of formula Bi1.5-xMxSb1.5-xM'xZnO7 (M= Fe; M'=Fe, Cr) (x=0; 0.10; 0.15) are prepared from simple oxides at 1080°C by using the ceramic method. All the crystal phases are indexed in the cubic system (space group; No.227). Rietveld refinement method of the Bi1.5Sb1.5ZnO7 (x=0) compounds using powder XRD analysis confirms an overall A2B2O7 cubic pyrochlore structure according to B i 1 . 5 3 + Z n 0 . 5 2 + S b 1 . 5 5 + Z n 0 . 5 2 + O 7 formula with 10.44425(3) Å and F d 3 ¯ m space group. The substitution of Bi(III) and Sb(V) by Fe(III) and Cr(III) in the Bi1.5Sb1.5ZnO7 phase shows the appearance of solid solutions limited to x=0.15. The variation of the cell’s parameter is recorded to the element’s ionic radii. The paramagnetic character is observed in all substituted compounds. The measurements of the electrical conductivity as a function of the temperature, make evidence of the semi-conductive property. Whilst, the magnetic susceptibility satisfies the modified Curie Weiss (CW) and shows the magnetic behavior due to the magnetic moments of the iron and chromium ions being involved in the synthesis of the compounds. Besides, the UV-Visible reflectance displays light absorption in the visible domain.

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BACKGROUND: This study aims to evaluate the stress distribution in peri-implant bone, implant surfaces, and within the framework material under vertical and oblique loads, considering various angulations and abutment types of bendable one-piece implants in the All-on-4 concept. METHODS: A three-dimensional model of an edentulous mandible was constructed. Six different configurations were modeled according to prosthesis connection type and inclination of the posterior implants based on the All-on-4 protocol. Four one-piece implants were placed in each model and a cobalt-chromium frameworks with 14 mm cantilever lengths were designed. Under vertical and oblique loading conditions, maximum principal stress and minimum principal stress values were obtained for cortical and trabecular bone and von Mises stress values were calculated for implants and frameworks. RESULTS: Implant angulation, connection type, and loading conditions affected stress distribution in the peri-implant bone, implants, and frameworks. Higher stress values were observed in posterior implants with increased angulation. Screw-retained models demonstrated greater stress values compared to cement-retained ones under both loading conditions. CONCLUSIONS: For optimal stress distribution in peri-implant bone and frameworks, cement-retained prosthesis may be preferred, especially in cases with increased implant angulation in one-piece bendable systems. Additionally, careful consideration of posterior implant angulation and loading conditions is crucial to minimize the excessive stress and to enhance long-term stability. CLINICAL TRIAL NUMBER: Not applicable.

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Background: Well articulated by John Knowles - "Everything has to evolve or else it perishes." With the paradigm shift of emphasis toward the prevention of dental caries, it has been proven that laser irradiation protects against both caries initiation and caries progression. Aim: The aim of the study was to evaluate and compare the micromorphology of caries-free extracted premolars using a Scanning electron microscope (SEM) after fissurotomy by conventional fissurotomy bur and erbium, chromium: yttrium, scandium, gallium, and garnet (ER, CR: YSGG) hard-tissue laser. Methodology: Sixty caries-free premolars extracted atraumatically for orthodontic treatment were included in the study. The samples were divided into two groups randomly (Group 1: fissurotomy by bur, n = 30, and Group 2: fissurotomy by hard-tissue laser, n = 30). Each sample was further divided into halves from the occlusal surface wherein one-half of the occlusal surface received fissurotomy procedure and the other half was control. Samples were analyzed by scanning electron microscopy (SEM) for micromorphological changes. Results: Profile image of control samples revealed the disorganization of enamel surface at the junction of fissures forming a heterogeneous tissue and agglomeration of enamel with deep pit and fissure. On the contrary, the image of experimented samples (with laser fissurotomy) showed smooth enamel surface and homogeneous enamel subsurface with wider pit and fissure owing to self-cleansing ability. Conclusion: On the grounds of the present study results, it could be concluded that the intervention of ER, CR: YSGG hard-tissue laser possesses self-cleansable pit and fissures for caries prevention and has the potential to irradicate the smear layer entirely for superior attachment of remineralizing agents.

Abstract licence: CC BY-NC-SA