What should I avoid while taking Bosentan 125mg tablets?

Take with or without food. The absorption is unaffected by food. (Source: DrugBank, licensed under CC BY-NC 4.0)

Do I need a prescription for Bosentan 125mg tablets?

Bosentan 125mg tablets is classified as a Valid as a prescribable product in the UK. However, always consult a pharmacist or doctor before use. (Source: NHS dm+d)

What are the brand names for Bosentan 125mg tablets?

Bosentan 125mg tablets is the generic name. It is available under brand names including: Bosentan 125mg tablets, Bosentan 125mg tablets, Bosentan 125mg tablets, Bosentan 125mg tablets, Bosentan 125mg tablets and 3 more. (Source: NHS dm+d — Actual Medicinal Products)

Bosentan 125mg tablets

Prescription only

Requires a prescription from a doctor or prescriber

Tablet

125mg

Oral

Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals.

Active ingredients:

Bosentan

BNF classificationBrowse formulary

Where this medicine sits in the British National Formulary — the UK's standard prescribing reference

BNF 02.05.01

ATC classificationBrowse ATC index

International classification by the WHO, grouping medicines by the organ system they act on

ATC C02KX01

Chemical classBrowse classes

Classification based on the molecule's chemical structure and properties

Check interactions for Bosentan

No active safety alerts

Official documents, adverse reaction reporting, and safety monitoring

Report a side effect

Submit a Yellow Card report to the MHRA

Official medicine documents

Yellow Card

Report side effects (MHRA)

Drug safety updates

MHRA alerts for Bosentan

Source: MHRA Products DatabaseOGL 3.0

Updated 3 months ago(16 Jan 2026)

Safety monitoring data

Yellow Card reports

MHRA

The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.

View Drug Analysis Profile

Suspected adverse reactions reported for Bosentan

Browse all iDAP reports

Interactive Drug Analysis Profiles for all medicines

Report a side effect

Submit a Yellow Card report to the MHRA

Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.

EudraVigilance

EMA

The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.

View EudraVigilance report

Suspected adverse reactions reported for Bosentan

About EudraVigilance

Learn about EU pharmacovigilance and safety monitoring

EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.

8 branded products available

8 productsShow details

8 products

Possibly available on the UK marketDiscontinuedAvailability per NHS dm+d

MHRA licensed products

View all licensed products for Bosentan on the MHRA register

Bosentan 125mg tablets

Viatris UK Healthcare Ltd

Bosentan 125mg tablets

Milpharm Ltd

Bosentan 125mg tablets

Accord-UK Ltd

Bosentan 125mg tablets

Cipla EU Ltd

Stayveer 125mg tablets

Advanz Pharma

Discontinued

Tracleer 125mg tablets

Janssen-Cilag Ltd

Discontinued

Bosentan 125mg tablets

Zentiva Pharma UK Ltd

Discontinued

Bosentan 125mg tablets

Dr Reddy's Laboratories (UK) Ltd

Discontinued

Source: NHS dm+dOGL 3.0

Updated about 1 month ago(1 Mar 2026)

Daily doseShow details

WHO defined daily dose (DDD)

250 mg

Not a recommended dose. The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. It is a statistical measure used for research and comparison purposes only.

Source: WHO Collaborating Centre for Drug Statistics Methodology, distributed via NHS dm+d BNF mapping files. Contains public sector information licensed under the Open Government Licence v3.0.

Therapeutically similar medicines

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Injection

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Same therapeutic group

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Injection

60mg

Same therapeutic group

Macitentan 2.5mg dispersible tablets sugar free

Tablet

2.5mg

Same therapeutic group

Ambrisentan 2.5mg tablets

Tablet

2.5mg

Same therapeutic group

Riociguat 500microgram tablets

Tablet

Same therapeutic group

Similarity based on WHO Anatomical Therapeutic Chemical (ATC) classification and NHS BNF section grouping. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.

NHS prescribing volume and spending trends

Show details

Loading prescribing data...

Clinical guidelines and formulary information

British National Formulary

Bosentan

BNF

Drug monograph — bnf.nice.org.uk

Source: British National Formulary, NICE. Joint Formulary Committee. Contains public sector information licensed under the Open Government Licence v3.0.

NICE clinical guidance(2)

Digital ulcers: sildenafil (ESUOM42)

ESUOM42

Evidence summary

Updated Mar 2015

Idiopathic pulmonary fibrosis in adults: diagnosis and management (CG163)

CG163

Clinical guideline

Updated May 2017

Source: National Institute for Health and Care Excellence (NICE). Contains public sector information licensed under the Open Government Licence v3.0.

Check stock at pharmacies and supply information

Show details

Pharmacy stock checkers

Search for this medicine at major UK pharmacy chains. These links open the retailer's own website — results depend on their current online catalogue.

Boots

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Lloyds

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DeliveryNHS

P2U

Pharmacy2U

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DeliveryNHS

Supply & product information

Official product databases and supply status monitoring

Shortages info

NHS Specialist Pharmacy Service (SPS)

emc product search

Discontinuations & alternatives for Bosentan

Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. emc (electronic medicines compendium) is operated by Datapharm Ltd. Shortage information sourced from NHS Specialist Pharmacy Service (SPS), sps.nhs.uk.

Codes for healthcare professionals and prescribing systems

Show details

These codes are used by healthcare IT systems and prescribers to identify this medicine.

NHS UK identifiers

SNOMED CT

39733911000001105

dm+d ID

39733911000001105

VTM (Virtual Therapeutic Moiety)

774891004

VMP (Virtual Medicinal Product)

39733911000001105

BNF code

02050100

International identifiers

ATC code — Anatomical Therapeutic Chemical (WHO)

C02KX01

Browse tools

dm+d Browser

NHSBSA medicines dictionary lookup

SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF codes from NHS Business Services Authority (NHSBSA). ATC codes from the WHO Collaborating Centre for Drug Statistics Methodology (whocc.no).

Active and completed clinical studies from ClinicalTrials.gov

Show details

Searching UK clinical trials...

Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.

Pharmacology and chemical data from DrugBank

go.drugbank.com

Key facts

Drug status

Approved

Major interactions

5 found

Half-life

5 hours

Mechanism

Endothelin-1 (ET-1) is a neurohormone, the effects of which are mediated by bind…

Food interactions

1 warning

Human targets

2 targets

Data: DrugBank · CC BY-NC 4.0

Pharmacokinetics at a glance

Absorption

50%

Absolute bioavailability is approximately 50% and food does not affect absorption.

Half-life

5 hours

Terminal elimination half-life is about 5 hours in healthy adult subjects.

Protein binding

98%

Greater than 98% to plasma proteins, mainly albumin.

Volume of distribution

18 L

* 18 L

Metabolism

10 to 20%

Bosentan is metabolized in the liver by the cytochrome P450 enzymes CYP2C9 and CYP3A4 (and possibly CYP2C19), producing three metabolites, one…

Elimination

Bosentan is eliminated by biliary excretion following metabolism in the liver.

Clearance

4 L/h

* 4 L/h [patients with pulmonary arterial hypertension]

Pharmacokinetic data: DrugBank · CC BY-NC 4.0

Status:

Approved

Investigational

Small molecule

About this compound

Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.

Properties:

solid

Avg. mass: 551.61 Da

View FDA drug label

DrugBank indication

Used in the treatment of pulmonary arterial hypertension (PAH), to improve exercise ability and to decrease the rate of clinical worsening (in patients with WHO Class III or IV symptoms).

Also known as(46)

4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide

bosentán

Bosentan

bosentan anhydrous

bosentanum

p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide

Endothelin receptor non-selective type

ET-B

Dosage forms(34)

Tablet (Oral) — 125.00 mg

Tablet (Oral) — 125.0 mg

Tablet (Oral) — 125 mg/1

Tablet (Oral) — 62.5 mg/1

Tablet, coated (Oral) — 125 mg/1

Tablet, coated (Oral) — 62.5 mg/1

Tablet, film coated (Oral) — 125 mg/1

Tablet, film coated (Oral) — 62.5 mg/1

Molecular properties(19)

Drug interactions(1262)

Known interactions with other medications. Always consult a healthcare professional.

Cyclosporine

Unknown severity

DB00091

The serum concentration of Bosentan can be increased when it is combined with Cyclosporine.

Check this interaction

Glycochenodeoxycholic Acid

Moderate

DB02123

Bosentan may decrease the excretion rate of Glycochenodeoxycholic Acid which could result in a higher serum level.

Check this interaction

Fluvoxamine

Moderate

DB00176

Bosentan may decrease the excretion rate of Fluvoxamine which could result in a higher serum level.

Check this interaction

Glimepiride

Moderate

DB00222

Bosentan may decrease the excretion rate of Glimepiride which could result in a higher serum level.

Check this interaction

Isradipine

Moderate

DB00270

Bosentan may decrease the excretion rate of Isradipine which could result in a higher serum level.

Check this interaction

Flucloxacillin

Moderate

DB00301

Bosentan may decrease the excretion rate of Flucloxacillin which could result in a higher serum level.

Check this interaction

Indomethacin

Moderate

DB00328

Bosentan may decrease the excretion rate of Indomethacin which could result in a higher serum level.

Check this interaction

Atenolol

Moderate

DB00335

Bosentan may decrease the excretion rate of Atenolol which could result in a higher serum level.

Check this interaction

Rosiglitazone

Moderate

DB00412

Bosentan may decrease the excretion rate of Rosiglitazone which could result in a higher serum level.

Check this interaction

Spironolactone

Moderate

DB00421

Spironolactone may increase the hypotensive activities of Bosentan.

Check this interaction

Cerivastatin

Moderate

DB00439

Bosentan may decrease the excretion rate of Cerivastatin which could result in a higher serum level.

Check this interaction

Loratadine

Moderate

DB00455

Bosentan may decrease the excretion rate of Loratadine which could result in a higher serum level.

Check this interaction

Atropine

Moderate

DB00572

Bosentan may decrease the excretion rate of Atropine which could result in a higher serum level.

Check this interaction

Diclofenac

Moderate

DB00586

Bosentan may decrease the excretion rate of Diclofenac which could result in a higher serum level.

Check this interaction

Losartan

Moderate

DB00678

The metabolism of Losartan can be increased when combined with Bosentan.

Check this interaction

Fluorescein

Moderate

DB00693

Bosentan may decrease the excretion rate of Fluorescein which could result in a higher serum level.

Check this interaction

Nitrofurantoin

Moderate

DB00698

Bosentan may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.

Check this interaction

Naproxen

Moderate

DB00788

Bosentan may decrease the excretion rate of Naproxen which could result in a higher serum level.

Check this interaction

Disulfiram

Moderate

DB00822

Bosentan may decrease the excretion rate of Disulfiram which could result in a higher serum level.

Check this interaction

Cefaclor

Moderate

DB00833

Bosentan may decrease the excretion rate of Cefaclor which could result in a higher serum level.

Check this interaction

Tinidazole

Moderate

DB00911

Bosentan may decrease the excretion rate of Tinidazole which could result in a higher serum level.

Check this interaction

Repaglinide

Moderate

DB00912

Bosentan may decrease the excretion rate of Repaglinide which could result in a higher serum level.

Check this interaction

Telmisartan

Moderate

DB00966

Bosentan may decrease the excretion rate of Telmisartan which could result in a higher serum level.

Check this interaction

Ezetimibe

Moderate

DB00973

Bosentan may decrease the excretion rate of Ezetimibe which could result in a higher serum level.

Check this interaction

Dipyridamole

Moderate

DB00975

Bosentan may decrease the excretion rate of Dipyridamole which could result in a higher serum level.

Check this interaction

Sulfamethoxazole

Moderate

DB01015

Bosentan may decrease the excretion rate of Sulfamethoxazole which could result in a higher serum level.

Check this interaction

Fenofibrate

Moderate

DB01039

Bosentan may decrease the excretion rate of Fenofibrate which could result in a higher serum level.

Check this interaction

Nitrendipine

Moderate

DB01054

Bosentan may decrease the excretion rate of Nitrendipine which could result in a higher serum level.

Check this interaction

Glipizide

Moderate

DB01067

Bosentan may decrease the excretion rate of Glipizide which could result in a higher serum level.

Check this interaction

Sulfinpyrazone

Moderate

DB01138

Bosentan may decrease the excretion rate of Sulfinpyrazone which could result in a higher serum level.

Check this interaction

Ofloxacin

Moderate

DB01165

Bosentan may decrease the excretion rate of Ofloxacin which could result in a higher serum level.

Check this interaction

Taurocholic acid

Moderate

DB04348

Bosentan may decrease the excretion rate of Taurocholic acid which could result in a higher serum level.

Check this interaction

Prasterone sulfate

Moderate

DB05804

Bosentan may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level.

Check this interaction

Indocyanine green acid form

Moderate

DB09374

Bosentan may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level.

Check this interaction

Benzbromarone

Moderate

DB12319

Bosentan may decrease the excretion rate of Benzbromarone which could result in a higher serum level.

Check this interaction

Pilsicainide

Moderate

DB12712

Bosentan may decrease the excretion rate of Pilsicainide which could result in a higher serum level.

Check this interaction

Dihydroergocristine

Moderate

DB13345

Bosentan may decrease the excretion rate of Dihydroergocristine which could result in a higher serum level.

Check this interaction

Glycyrrhizic acid

Moderate

DB13751

Bosentan may decrease the excretion rate of Glycyrrhizic acid which could result in a higher serum level.

Check this interaction

Nifedipine

Moderate

DB01115

Bosentan may decrease the excretion rate of Nifedipine which could result in a higher serum level.

Check this interaction

Budesonide

Moderate

DB01222

Bosentan may decrease the excretion rate of Budesonide which could result in a higher serum level.

Check this interaction

Belantamab mafodotin

Moderate

DB15719

Bosentan may decrease the excretion rate of Belantamab mafodotin which could result in a higher serum level.

Check this interaction

Aripiprazole

Moderate

DB01238

The metabolism of Aripiprazole can be increased when combined with Bosentan.

Check this interaction

Aripiprazole lauroxil

Moderate

DB14185

The metabolism of Aripiprazole lauroxil can be increased when combined with Bosentan.

Check this interaction

Alfuzosin

Moderate

DB00346

Alfuzosin may increase the hypotensive activities of Bosentan.

Check this interaction

Amifostine

Moderate

DB01143

Bosentan may increase the hypotensive activities of Amifostine.

Check this interaction

Diazoxide

Moderate

DB01119

Diazoxide may increase the hypotensive activities of Bosentan.

Check this interaction

Methylphenidate

Moderate

DB00422

Methylphenidate may decrease the antihypertensive activities of Bosentan.

Check this interaction

Dexmethylphenidate

Moderate

DB06701

Dexmethylphenidate may decrease the antihypertensive activities of Bosentan.

Check this interaction

Obinutuzumab

Moderate

DB08935

Bosentan may increase the hypotensive activities of Obinutuzumab.

Check this interaction

Pentoxifylline

Moderate

DB00806

Pentoxifylline may increase the hypotensive activities of Bosentan.

Check this interaction

Showing 50 of 1262 interactions

Food & lifestyle interactions

Advice

Take with or without food. The absorption is unaffected by food.

Toxicity & overdose

Bosentan has been given as a single dose of up to 2400 mg in normal volunteers, or up to 2000 mg/day for 2 months in patients, without any major clinical consequences. The most common side effect was headache of mild to moderate intensity. In the cyclosporine A interaction study, in which doses of 500 and 1000 mg b.i.d. of bosentan were given concomitantly with cyclosporine A, trough plasma concentrations of bosentan increased 30-fold, resulting in severe headache, nausea, and vomiting, but no serious adverse events.

Mild decreases in blood pressure and increases in heart rate were observed. There is no specific experience of overdosage with bosentan beyond the doses described above. Massive overdosage may result in pronounced hypotension requiring active cardiovascular support.

How it works

Mechanism of action

Endothelin-1 (ET-1) is a neurohormone, the effects of which are mediated by binding to ET_A and ET_B receptors in the endothelium and vascular smooth muscle. It displays a slightly higher affinity towards ET_A receptors than ET_B receptors. ET-1 concentrations are elevated in plasma and lung tissue of patients with pulmonary arterial hypertension, suggesting a pathogenic role for ET-1 in this disease. Bosentan is a specific and competitive antagonist at endothelin receptor types ET_A and ET_B.

Pharmacodynamics

Bosentan belongs to a class of drugs known as endothelin receptor antagonists (ERAs). Patients with PAH have elevated levels of endothelin, a potent blood vessel constrictor, in their plasma and lung tissue. Bosentan blocks the binding of endothelin to its receptors, thereby negating endothelin's deleterious effects.

Pharmacokinetics

How the body processes this drug — absorption, distribution, metabolism, and elimination

Absorption

Absolute bioavailability is approximately 50% and food does not affect absorption.

Half-life

Terminal elimination half-life is about 5 hours in healthy adult subjects.

Protein binding

Greater than 98% to plasma proteins, mainly albumin.

Volume of distribution

* 18 L

Metabolism

Bosentan is metabolized in the liver by the cytochrome P450 enzymes CYP2C9 and CYP3A4 (and possibly CYP2C19), producing three metabolites, one of which, Ro 48-5033, is pharmacologically active and may contribute 10 to 20% to the total activity of the parent compound.

Route of elimination

Bosentan is eliminated by biliary excretion following metabolism in the liver.

Clearance

* 4 L/h [patients with pulmonary arterial hypertension]

Drug targets(2)

Proteins and enzymes this drug interacts with in the body

Endothelin receptor type B

BE0000043

EDNRB

antagonist

Specific functionendothelin receptor activity

Cellular location

Cell membrane

General function & pharmacology

Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system

Endothelin-1 receptor

BE0000521

EDNRA

antagonist

Specific functionendothelin receptor activity

Cellular location

Cell membrane

General function & pharmacology

Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3

Metabolizing enzymes(2)

Enzymes involved in drug metabolism — important for understanding drug interactions

Enzyme activity key

substrate

inhibitor

inducer

CYP3A4Cytochrome P450 3A4

substrate

inducer

CYP2C9Cytochrome P450 2C9

substrate

inducer

Transporters(1)

Proteins that transport this drug across cell membranes

Bile salt export pump

BE0000703

ABCB11

inhibitor

Specific functionABC-type bile acid transporter activity

Cellular location

Apical cell membrane

General function & pharmacology

Catalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates in hepatic bile acid homeostasis and consequently to lipid homeostasis through regulation of biliary lipid secretion in a bile salts dependent manner .
PMID:15791618 PMID:16332456 PMID:18985798 PMID:19228692 PMID:20010382 PMID:20398791 PMID:22262466 PMID:24711118 PMID:29507376 PMID:32203132

Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts .
PMID:16332456
Also transports non-bile acid compounds, such as pravastatin and fexofenadine in an ATP-dependent manner and may be involved in their biliary excretion PMID:15901796 PMID:18245269

ATC classification(2 codes)

ATC G01AE10

ATC C02KX01

Affected organisms(1)

Humans and other mammals

Salt forms(1)

Bosentan monohydrate(DBSALT001842)

Experimental properties(3)

External resources(2)

RxList Drugs.com

Protein Data Bank entries(1)

5xpr

Commercial products(77)

Chemical identifiers

CAS, UNII, InChI Key and database cross-references

Show

Linked compound data from DrugBank Open Data (CC BY-NC 4.0)

Bosentan

DB00559

CAS number

147536-97-8

UNII (FDA)

XUL93R30K2

InChI Key (molecular fingerprint)

GJPICJJJRGTNOD-UHFFFAOYSA-N

Additional database identifiers

Drugs Product Database (DPD)

12538

ChEBI

51450

PubChem Compound

104865

PubChem Substance

46507154

KEGG Drug

D01227

ChemSpider

94651

BindingDB

50061101

PharmGKB

PA10034

PDB

K86

Therapeutic Targets Database

DNC000341

Wikipedia

Bosentan

ChEMBL

CHEMBL957

ZINC

ZINC000001538857

RxCUI

75207

HUGO Gene Nomenclature Committee (HGNC)

HGNC:3180

GenAtlas

EDNRB

GeneCards

EDNRB

GenBank Gene Database

M74921

GenBank Protein Database

182276

IUPHAR

220

Guide to Pharmacology

220

UniProtKB

P24530

UniProt Accession

EDNRB_HUMAN

HUGO Gene Nomenclature Committee (HGNC)

HGNC:3179

GenAtlas

EDNRA

GeneCards

EDNRA

GenBank Gene Database

S63938

GenBank Protein Database

238636

IUPHAR

219

Guide to Pharmacology

219

UniProtKB

P25101

UniProt Accession

EDNRA_HUMAN

HUGO Gene Nomenclature Committee (HGNC)

HGNC:2637

GenAtlas

CYP3A4

GeneCards

CYP3A4

GenBank Gene Database

M18907

Guide to Pharmacology

1337

UniProtKB

P08684

UniProt Accession

CP3A4_HUMAN

HUGO Gene Nomenclature Committee (HGNC)

HGNC:2623

GenAtlas

CYP2C9

GeneCards

CYP2C9

GenBank Gene Database

AY341248

Guide to Pharmacology

1326

UniProtKB

P11712

UniProt Accession

CP2C9_HUMAN

HUGO Gene Nomenclature Committee (HGNC)

HGNC:42

GenAtlas

ABCB11

GeneCards

ABCB11

GenBank Gene Database

AF091582

GenBank Protein Database

3873243

Guide to Pharmacology

778

UniProtKB

O95342

UniProt Accession

ABCBB_HUMAN

Patent information

2 active patents, 2 expired

7959945

United States

Approved 14 Jun 2011 · Expires 28 Dec 2027

1y 8m

8309126

United States

Approved 13 Nov 2012 · Expires 15 May 2026

1 months

5292740

United States

Approved 8 Mar 1994 · Expires 20 Nov 2015

Expired

2071193

Canada

Approved 25 Aug 1998 · Expires 12 Jun 2012

Expired

The earliest active patent expires May 2026. Generic versions may become available after this date.

Source: DrugBank · CC BY-NC 4.0. Patent data sourced from national patent offices. Expiry dates may not reflect extensions, regulatory exclusivity periods, or legal challenges.

DrugBank citations

If you use DrugBank data in your research, please cite the following publications:

Knox C., Wilson M., Klinger C.M., et al

DrugBank 6.

0: the DrugBank Knowledgebase for 2024

Nucleic Acids Res. 2024 Jan 552(D1):D1265-D1275

PMID: 37953279

Wishart D.S., Feunang Y.D., Guo A.C., et al

DrugBank 5.

0: a major update to the DrugBank database for 2018

Nucleic Acids Res. 2017 Nov 846(D1):D1074-D1082

PMID: 29126136

Show earlier publications

Law V., Knox C., Djoumbou Y., et al

DrugBank 4.

0: shedding new light on drug metabolism

Nucleic Acids Res. 2014 Jan 142(1):D1091-7

PMID: 24203711

Knox C., Law V., Jewison T., et al

DrugBank 3.

0: a comprehensive resource for 'omics' research on drugs

Nucleic Acids Res. 2011 Jan39(Database issue):D1035-41

PMID: 21059682

Wishart D.S., Knox C., Guo A.C., et al

DrugBank: a knowledgebase for drugs, drug actions and drug targets.

Nucleic Acids Research

2008 Jan36(Database issue):D901-6

PMID: 18048412

Wishart D.S., Knox C., Guo A.C., et al

DrugBank: a comprehensive resource for in silico drug discovery and exploration.

Nucleic Acids Research

2006 Jan 134(Database issue):D668-72

PMID: 16381955

Source: go.drugbank.comCC BY-NC 4.0

Updated about 1 month ago(4 Mar 2026)

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Bosentan 125mg tablets

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Bosentan 125mg tablets

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Bosentan

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