Boric acid 300mg vaginal capsules
Requires a prescription from a doctor or prescriber
Boric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical formula H3BO3.
Official documents, adverse reaction reporting, and safety monitoring
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Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
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Suspected adverse reactions reported for Boric acid
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Report a side effect
Submit a Yellow Card report to the MHRA
Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.
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Suspected adverse reactions reported for Boric acid
About EudraVigilance
Learn about EU pharmacovigilance and safety monitoring
EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
1 branded products available
Guidelines from the National Institute for Health and Care Excellence
NICE clinical guidance(1)
Source: National Institute for Health and Care Excellence (NICE). Contains public sector information licensed under the Open Government Licence v3.0.
Check stock at pharmacies and supply information
Pharmacy stock checkers
Search for this medicine at major UK pharmacy chains. These links open the retailer's own website — results depend on their current online catalogue.
Supply & safety information
Official UK regulator monitoring and safety alerts
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. Shortage and safety information sourced from MHRA drug safety updates (gov.uk, Crown Copyright under OGL v3.0).
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF code shown is the factual mapping value distributed by NHS Business Services Authority (NHSBSA) in the dm+d supplementary file under OGL v3.0; it is not affiliated with, nor licensed from, the publishers of the British National Formulary.
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing all 30 studies.
Reviews & meta-analyses: 2 · 2019–2025
Showing all 30 studies, sorted by most relevant.
Wei Li, Wan Zhou, Zhishan Zhou, et al.
Angewandte Chemie, 2019
N. Hadrup, M. Frederiksen, A. Sharma
Regulatory toxicology and pharmacology : RTP, 2021
- Administration, Cutaneous
- Administration, Inhalation
- Boron Compounds
A. Lopalco, A. Lopedota, V. Laquintana, et al.
Journal of pharmaceutical sciences, 2020
- Boric Acids
- Lewis Acids
- Alcohols
J. Woo, N. Kim, Seongbeen Kim, et al.
Composites Part B-engineering, 2020
Huanxin Guo, Cong Liu, Honglong Hu, et al.
National Science Review, 2023
Bihe Yuan, Y. Wang, Gongqing Chen, et al.
Journal of hazardous materials, 2020
Haoyue Zheng, P. Cao, Yanying Wang, et al.
Angewandte Chemie, 2021
A. M. Zayed, M. A. Masoud, M. Shahien, et al.
Construction and Building Materials, 2020
Chaochao Cao, Yanming Xue, Zhenya Liu, et al.
2D Materials, 2019
H. Yoğurtçu, N. Gürler
Polymer Engineering & Science, 2024
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
None known
Half-life
13 to 24 hours
Mechanism
Information regarding the mechanism of action of boric acid in mediating its ant…
Food interactions
None known
Human targets
None mapped
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Absorption
1.0-1.5 hr
[L2140]…
Half-life
13 to 24 hours
[A32450][L2140]
Protein binding
Volume of distribution
0.17 to 0.5 L/kg
[L2140]
Metabolism
Elimination
90%
Clearance
0.99 L/h
Pharmacokinetic data: DrugBank · CC BY-NC 4.0
Systemic effects from boric acid poisoning usually occur from multiple exposures over a period of days and involve gastrointestinal, dermal, CNS, and renal manifestations. Gastrointestinal toxicity include persistent nausea, vomiting, diarrhea, epigastric pain, hematemesis, and blue-green discoloration of the feces and vomit .
[L2140]
Following the onset of GI symptoms, a characteristic intense generalized erythroderma follows .
[L2140]
Management of mild to moderate toxicity should be supportive. In case of severe toxicity, dialysis may be required in addition to supportive treatment.
How the body processes this drug — absorption, distribution, metabolism, and elimination
[L2140]
Following intraperitoneal injection in mice, the peak concentration was reached in about 1.0-1.5 hr in the brain whereas the value was 0.5 hr in other tissues .
[L2140]
[A32450][L2140]
[L2140]
[L2140]
[A32450]
ATC S02AA03
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
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Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Linked compound data from DrugBank Open Data (CC BY-NC 4.0)
Boric acid
DrugBank citations
If you use DrugBank data in your research, please cite the following publications:
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Structured knowledge from the free knowledge base
Molecular structure
Linked open data from Wikidata (Q187045), a free and open knowledge base operated by the Wikimedia Foundation. Data is available under the Creative Commons CC0 1.0 Public Domain Dedication. Molecular structure images from Wikimedia Commons.