Borage oil 1g capsules

Background:Coleus amboinicus (Lour.) (syn Plectranthus amboinicus) from the Lamiaceae family-a large family of aromatic herbs with many medicinally important species-is a frequently cited species within the Plectranthus genus, renowned for its traditional uses, phytochemical composition, biological activities, and applications in skin care. Methods: A systematic review was conducted following PRISMA guidelines to provide an in-depth understanding of P. amboinicus' phytochemical composition and biological activity, particularly in dermatological contexts, underscoring its significance in traditional medicine and modern phytochemical research. Results: P. amboinicus extracts and essential oils exhibit significant antimicrobial activity against both Gram-positive and Gram-negative bacteria, and notable antifungal properties, particularly against dermatophytes. Additionally, the species demonstrates remarkable mosquito repellent and anti-parasitic effects, comparable to DEET, and potent anti-inflammatory properties by inhibiting pro-inflammatory cytokines. The plant's rich polyphenolic content contributes to its significant antioxidant properties, preventing conditions like hyperpigmentation and premature aging. P. amboinicus also exhibits cytotoxic activity against various cancer cell lines and promotes wound healing through its analgesic, anti-inflammatory, and antioxidant abilities. Conclusions: This comprehensive exploration of P. amboinicus validates its diverse therapeutic potential across infectious diseases, oncology, and wound care. Further research and clinical trials are warranted to fully elucidate its mechanisms of action and optimize its therapeutic applications, paving the way for its integration into mainstream medical practices.

Abstract licence: CC BY

BackgroundIn recent years, there has been increasing interest in novel plant-based oil sources as sustainable alternatives to conventional edible oils. This shift is driven by consumer demand for natural, nutrient-dense, and health-promoting products. Among these, cold-pressed oils have gained prominence as specialty oils. Cold-press extraction is a mechanical, environmental friendly and energy-efficient technique that eliminates the use of heat and solvents, thereby preserving the natural physicochemical and nutritional properties of oils. This method is applied to seeds, kernels, fruits, and peels to obtain oils rich in bioactive compounds.Aim of the reviewThis systematic review aims to summarize and critically evaluate the extraction techniques, stability-enhancing strategies, physicochemical characteristics, nutritional composition, and pharmacological activities of various cold-pressed oils. It also highlights current research gaps to guide future investigations.MethodsRelevant literature was collected from scientific databases, including PubMed, Scopus, Web of Science, Google Scholar, and NCBI, as well as peer-reviewed journals. Additional gray literature, including web articles were also examined to ensure a comprehensive review of available information.ResultsCold-pressed oils retain significantly higher levels of polyunsaturated fatty acids, antioxidants, vitamins, and other bioactive compounds compared to refined oils due to minimal processing. These constituents contribute to enhanced biological activities, including antioxidant, anti-inflammatory, and anticancer properties. Consequently, cold-pressed oils exhibit improved nutritional quality and potential health benefits. However, their quality and shelf life are strongly influenced by factors, including the source of raw materials, plant genotype, harvest timing, moisture content, storage conditions, pre-processing steps, and extraction parameters. Oils rich in mono-and polyunsaturated fatty acids are particularly susceptible to oxidation, which can compromise stability and health benefits. To address this, various strategies, including the use of natural antioxidants, encapsulation, optimized storage conditions, and advanced extraction technologies, have been proposed to enhance oxidative stability.ConclusionCold-pressed oils offer valuable therapeutic and nutritional benefits due to their rich profile of bioactive compounds. Despite their potential, research gaps remain, in developing integrated approaches to maintain and enhance their stability, nutritional value, and pharmacological properties. Addressing these gaps is crucial for fully understanding and maximizing the health benefits of plant-based, cold-pressed oils.

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BackgroundSalacca zalacca (snake fruit) is rich in antioxidants, polyphenols, organic acids, and vitamin C. This study aimed to evaluate the effectiveness of body massage oil containing snake fruit extract, in conjunction with traditional Thai massage (TTM), on skin quality in healthy individuals.MethodsSeventy-one participants aged 18-35 years were randomly assigned to one of three groups: (1) control group (n = 23) receiving TTM without oil; (2) Treatment-1 group (n = 23) receiving TTM with pure coconut oil; and (3) Treatment-2 group (n = 25) receiving TTM with snake fruit extract-infused oil. All participants received 60-min massages once weekly for 12 weeks. Skin parameters including elasticity, moisture, melanin, and oiliness were assessed at the neck, back, arm, and leg regions.ResultsAfter 12 weeks, skin elasticity significantly improved at all assessed regions in all groups (p ConclusionMassage oil containing snake fruit extract demonstrated specific benefits in enhancing skin oiliness and localized moisture. However, it did not confer overall superiority over conventional coconut oil, while improvements in elasticity and melanin appeared to be primarily attributable to the massage technique itself.Trial registrationClinicalTrials.gov Identifier: NCT06227260.

Abstract licence: CC BY