Autologous human corneal epithelial cells 300,000-1.2million cells/3.8square cm living tissue equivalent
Requires a prescription from a doctor or prescriber
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MHRA alerts for Autologous human corneal epithelial cells
Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
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Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
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EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
1 branded products available
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Holoclar 300,000-1.2million cells/3.8square cm living tissue equivalent
Guidelines from the National Institute for Health and Care Excellence
NICE clinical guidance(1)
Source: National Institute for Health and Care Excellence (NICE). Contains public sector information licensed under the Open Government Licence v3.0.
Check stock at pharmacies and supply information
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Supply & safety information
Official UK regulator monitoring and safety alerts
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Codes for healthcare professionals and prescribing systems
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NHS UK identifiers
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. BNF code shown is the factual mapping value distributed by NHS Business Services Authority (NHSBSA) in the dm+d supplementary file under OGL v3.0; it is not affiliated with, nor licensed from, the publishers of the British National Formulary.
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing the 50 most relevant studies.
Reviews & meta-analyses: 5 · Randomised trials: 1 · 1989–2025
Showing the 50 most relevant studies, sorted by most relevant.
B A Noble
British Journal of Ophthalmology, 2004
- Analysis of Variance
- Fluorescent Dyes
- Keratoconjunctivitis Sicca
AlShammari AZAM, Khouqeer Z, Medani S, et al.
2025
Pertiwi AN, Susiyanti M
2025
Niveditha Pinnamaneni, James L. Funderburgh
Stem Cells, 2012
- Cell Differentiation
- Corneal Stroma
- Flow Cytometry
Hongyi Li, Yang Yang, Weiqi Hong, et al.
Signal Transduction and Targeted Therapy, 2020
- Gene Editing
- Genome, Human
- Genetic Diseases, Inborn
Yu Han, Yu Han, Xuezhou Li, et al.
Cells, 2019
- Cell Differentiation
- Regenerative Medicine
- Tissue Engineering
Carl Randall Harrell, Nemanja Jovičić, Valentin Djonov, et al.
Cells, 2019
- Extracellular Vesicles
- Inflammation
- Oxidative Stress
Tobias Hirsch, Tobias Rothoeft, Norbert Teig, et al.
Nature, 2017
- Epidermal Cells
- Cell Self Renewal
- Kalinin
Yuyi Han, Jianxin Yang, Jiankai Fang, et al.
Signal Transduction and Targeted Therapy, 2022
- Mesenchymal Stem Cells
- Cell Differentiation
- Cytokines
Hiroyuki Tomita, Kaori Tanaka, Takuji Tanaka, et al.
Oncotarget, 2016
- Aldehyde Dehydrogenase 1 Family
- Aldehyde Dehydrogenase
- Neoplasms
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Scientific data (pharmacology, interactions, ADME) is not yet available for this medicine. Clinical sections are sourced from the NHS dm+d database.