Aluminium hydroxide 475mg/5ml oral suspension
Requires a prescription from a doctor or prescriber
Aluminum hydroxide is an inorganic salt used as an antacid.
Official documents, adverse reaction reporting, and safety monitoring
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Submit a Yellow Card report to the MHRA
Official medicine documents
Yellow Card
Report side effects (MHRA)
Drug safety updates
MHRA alerts for Aluminium hydroxide
Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
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Suspected adverse reactions reported for Aluminium hydroxide
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Interactive Drug Analysis Profiles for all medicines
Report a side effect
Submit a Yellow Card report to the MHRA
Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.
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Suspected adverse reactions reported for Aluminium hydroxide
About EudraVigilance
Learn about EU pharmacovigilance and safety monitoring
EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
1 branded products available
Therapeutically similar medicines
Tablets & capsules
(2)Similarity is based on WHO Anatomical Therapeutic Chemical (ATC) classification and on a factual NHS dm+d therapeutic-grouping code prefix. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.
NHS prescribing volume and spending trends
Check stock at pharmacies and supply information
Pharmacy stock checkers
Search for this medicine at major UK pharmacy chains. These links open the retailer's own website — results depend on their current online catalogue.
Supply & safety information
Official UK regulator monitoring and safety alerts
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. Shortage and safety information sourced from MHRA drug safety updates (gov.uk, Crown Copyright under OGL v3.0).
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
Browse tools
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. ATC codes from the WHO Collaborating Centre for Drug Statistics Methodology (whocc.no).
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing the 50 most relevant studies.
Reviews & meta-analyses: 5 · Randomised trials: 4 · 1964–2026
Showing the 50 most relevant studies, sorted by most relevant.
Sonya Abraham, Helene Bæk Juel, Peter Fibiger Bang, et al.
The Lancet Infectious Diseases, 2019
- Immunogenicity, Vaccine
- Adjuvants, Immunologic
- Administration, Intranasal
Szu-Min Hsieh, Ming-Che Liu, Yen-Hsu Chen, et al.
The Lancet Respiratory Medicine, 2021
- COVID-19
- Adjuvants, Immunologic
- Aluminum Hydroxide
Doyon-Plourde P, Chong J, Abrams EM, et al.
2026
- Aluminum
- Vaccines
- Adjuvants, Immunologic
Daniel Krewski, Robert A. Yokel, Evert Nieboer, et al.
Journal of Toxicology and Environmental Health Part B, 2007
- Aluminum
- Aluminum Hydroxide
- Aluminum Oxide
Sean Bennett, James McCarty, Roshan Ramanathan, et al.
The Lancet Infectious Diseases, 2022
- Vaccines, Virus-Like Particle
- Chikungunya Fever
- Immunogenicity, Vaccine
Sabu A, Ramesh R
2026
L. Franchi, G. Núñez
European Journal of Immunology, 2008
- NLR Family, Pyrin Domain-Containing 3 Protein
- Adjuvants, Immunologic
- Aluminum Hydroxide
J. Brewer, M. Conacher, C. Hunter, et al.
Journal of immunology, 1999
- Adjuvants, Immunologic
- Aluminum Hydroxide
- Cells, Cultured
R. Gherardi, M. Coquet, P. Cherin, et al.
Brain : a journal of neurology, 2001
- Adjuvants, Immunologic
- Aluminum Hydroxide
- Inclusion Bodies
J. Mannhalter, H. Neychev, G. Zlabinger, et al.
Clinical and experimental immunology, 1985
- Adjuvants, Immunologic
- Aluminum Hydroxide
- Antigen-Presenting Cells
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
None known
Half-life
Not available
Mechanism
Aluminum hydroxide is a basic inorganic salt that acts by neutralizing hydrochloric acid in gastric secretions.
Food interactions
1 warning
Human targets
None mapped
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Absorption
17-30%
Metabolism
Elimination
Pharmacokinetic data: DrugBank · CC BY-NC 4.0
Known interactions with other medicines. Always consult a healthcare professional.
Showing 50 of 352 interactions
How the body processes this drug — absorption, distribution, metabolism, and elimination
ATC A02AB02
ATC A02AB01
ATC A02AD03
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
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Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Linked compound data from DrugBank Open Data (CC BY-NC 4.0)
DrugBank citations
If you use DrugBank data in your research, please cite:
- DrugBank 6.02024Recommended citationKnox C., Wilson M., Klinger C.M., et alDrugBank 6.0: the DrugBank Knowledgebase for 2024Nucleic Acids Res. 2024 Jan 552(D1):D1265-D1275
- DrugBank 5.02018Wishart D.S., Feunang Y.D., Guo A.C., et alDrugBank 5.0: a major update to the DrugBank database for 2018Nucleic Acids Res. 2017 Nov 846(D1):D1074-D1082
- DrugBank 4.02014Law V., Knox C., Djoumbou Y., et alDrugBank 4.0: shedding new light on drug metabolismNucleic Acids Res. 2014 Jan 142(1):D1091-7
- DrugBank 3.02011Knox C., Law V., Jewison T., et alDrugBank 3.0: a comprehensive resource for 'omics' research on drugsNucleic Acids Res. 2011 Jan39(Database issue):D1035-41
- DrugBank 2.02008Wishart D.S., Knox C., Guo A.C., et alDrugBank: a knowledgebase for drugs, drug actions and drug targets.Nucleic Acids Research2008 Jan36(Database issue):D901-6
- DrugBank 1.02006Wishart D.S., Knox C., Guo A.C., et alDrugBank: a comprehensive resource for in silico drug discovery and exploration.Nucleic Acids Research2006 Jan 134(Database issue):D668-72