Aluminium chloride 20% solution
Available from a pharmacy with pharmacist advice
Aluminum chloride is a chemical compound with the chemical formula AlCl3.
Official documents, adverse reaction reporting, and safety monitoring
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Official medicine documents
Yellow Card
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Drug safety updates
MHRA alerts for Aluminium chloride
Safety monitoring data
Yellow Card reports
The MHRA Yellow Card scheme collects reports of suspected side effects from healthcare professionals and patients. View the Drug Analysis Profile (iDAP) for real-world adverse reaction data.
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Suspected adverse reactions reported for Aluminium chloride
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Report a side effect
Submit a Yellow Card report to the MHRA
Data from the MHRA Yellow Card scheme. A reported reaction does not necessarily mean the medicine caused it. Contains public sector information licensed under the Open Government Licence v3.0.
EudraVigilance
The European Medicines Agency (EMA) collects suspected adverse reaction reports from across the EU/EEA through the EudraVigilance system. Search for safety data on this medicine.
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Suspected adverse reactions reported for Aluminium chloride
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EudraVigilance data is published by the European Medicines Agency (EMA). A suspected adverse reaction is not necessarily caused by the medicine.
3 branded products available
MHRA licensed products
View all licensed products for Aluminium chloride on the MHRA register
Anhydrol Forte 20% solution
Driclor 20% solution
This is the NHS Drug Tariff indicative price used for reimbursement purposes. It may not reflect the price paid by patients or pharmacies.
View full Drug TariffSource: NHS Drug Tariff via NHSBSA. Derived from dm+d VMPP (Virtual Medicinal Product Pack) pricing data. Contains public sector information licensed under the Open Government Licence v3.0.
Therapeutically similar medicines
Similarity is based on WHO Anatomical Therapeutic Chemical (ATC) classification and on a factual NHS dm+d therapeutic-grouping code prefix. Source data: NHS dm+d via TRUD (OGL v3.0), WHO ATC/DDD Index.
NHS prescribing volume and spending trends
Guidelines from the National Institute for Health and Care Excellence
NICE clinical guidance(3)
Transcutaneous microwave ablation for severe primary axillary hyperhidrosis (HTG458)
Endoscopic thoracic sympathectomy for primary hyperhidrosis of the upper limb (HTG339)
Glycopyrronium bromide cream for treating severe primary axillary hyperhidrosis (TA1175)
Source: National Institute for Health and Care Excellence (NICE). Contains public sector information licensed under the Open Government Licence v3.0.
Check stock at pharmacies and supply information
Pharmacy stock checkers
Search for this medicine at major UK pharmacy chains. These links open the retailer's own website — results depend on their current online catalogue.
Supply & safety information
Official UK regulator monitoring and safety alerts
Pharmacy links redirect to the retailer's own search and do not represent real-time stock levels. Shortage and safety information sourced from MHRA drug safety updates (gov.uk, Crown Copyright under OGL v3.0).
Codes for healthcare professionals and prescribing systems
These codes are used by healthcare IT systems and prescribers to identify this medicine.
NHS UK identifiers
Browse tools
SNOMED CT and dm+d codes from NHS TRUD (Technology Reference data Update Distribution), licensed under the Open Government Licence v3.0. ATC codes from the WHO Collaborating Centre for Drug Statistics Methodology (whocc.no).
Active and completed clinical studies from ClinicalTrials.gov
Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (NLM), National Institutes of Health (NIH). Data accessed via ClinicalTrials.gov API v2. Trial information is provided for research purposes and does not constitute medical advice.
Academic studies and reviews for this medicine's active substance
Showing the 50 most relevant studies.
Reviews & meta-analyses: 3 · Randomised trials: 2 · 1978–2024
Showing the 50 most relevant studies, sorted by most relevant.
T. Jiang, M.J. Chollier Brym, G. Dubé, et al.
Surface and Coatings Technology, 2006
H. A. Ellis, J. H. McCarthy, J. Herrington
Journal of Clinical Pathology, 1979
S. De, S. Dutta, B. Saha
Green Chemistry, 2011
M. Yousef, A. Salama
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009
Arokiasamy Justin Thenmozhi, Tharsius Raja William Raja, T. Manivasagam, et al.
Nutritional Neuroscience, 2017
- Disease Models, Animal
- Dietary Supplements
- Cerebellum
A. Thenmozhi, T. Raja, U. Janakiraman, et al.
Neurochemical Research, 2015
- Rats
- Rats, Wistar
- Alzheimer Disease
Niall Mc Goldrick, Carly Ross, James Nelson
Evidence-Based Dentistry, 2017
- Aluminum Compounds
- Chlorides
- Epinephrine
M. Lavanya, Joydeep Ghosal, P. Rao
Canadian Metallurgical Quarterly, 2023
S. M. Chiroma, M. A. Mohd Moklas, C. N. Mat Taib, et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018
- Hippocampus
- Neurons
- Rats, Wistar
M. Streker, T. Reuther, Linda Hagen, et al.
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2012
Sources: aggregated from Europe PMC (EMBL-EBI), OpenAlex, Crossref, PubMed and other open scholarly databases. Retracted articles are excluded. Study information is provided for research purposes and does not constitute medical advice.
Pharmacology and chemical data from DrugBank
Key facts
Drug status
Approved
Major interactions
None known
Half-life
0.47 h
Mechanism
Aluminum chloride is commonly used topical antiperspirant.
Food interactions
None known
Human targets
1 target
Data: DrugBank · CC BY-NC 4.0
Pharmacokinetics at a glance
Absorption
17-30 %
[L2013]
…
Half-life
8.1 mg/k
[A32367]
Protein binding
8.1 mg/k
[A32367]
Volume of distribution
8.1 mg/k
[A32367]
Metabolism
Elimination
[L2013]
…
Clearance
8.1 mg/k
[A32367]
Pharmacokinetic data: DrugBank · CC BY-NC 4.0
- Indicated to reduce underarm perspiration.
Known interactions with other medicines. Always consult a healthcare professional.
Showing 29 of 29 interactions
[L2013]
Liver damage has been reported in acute and chronic toxicity of aluminum .
[L2013]
How the body processes this drug — absorption, distribution, metabolism, and elimination
[L2013]
In rabbits, administration of a single maximum safe oral dose aluminum chloride (333 mg Al/kg) resulted in aluminum absorption of 0.57 % .
[L2013]
Aluminum chloride may be absorbed via dermal route, with the uptake increasing in the microgram range but with an upper limit .
[L2013]
[A32367]
[A32367]
[A32367]
[L2013]
[L2013]
Aluminum chloride may be absorbed dermally.
[A32367]
Proteins and enzymes this drug interacts with in the body
PMID:11032875 PMID:11254391 PMID:16023112 PMID:16959573
Plays a role in insulin homeostasis .
PMID:11297618 PMID:9571255
May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity)
ATC D10AX01
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Show
Chemical identifiers
CAS, UNII, InChI Key and database cross-references
Linked compound data from DrugBank Open Data (CC BY-NC 4.0)
Aluminum chloride
Matched from: Aluminium chloride
Additional database identifiers
Drugs Product Database (DPD)
5821
ChemSpider
22445
HUGO Gene Nomenclature Committee (HGNC)
HGNC:4335
GenAtlas
GLUD1
GeneCards
GLUD1
GenBank Gene Database
X07674
GenBank Protein Database
31707
UniProt Accession
DHE3_HUMAN
DrugBank citations
If you use DrugBank data in your research, please cite:
- DrugBank 6.02024Recommended citationKnox C., Wilson M., Klinger C.M., et alDrugBank 6.0: the DrugBank Knowledgebase for 2024Nucleic Acids Res. 2024 Jan 552(D1):D1265-D1275
- DrugBank 5.02018Wishart D.S., Feunang Y.D., Guo A.C., et alDrugBank 5.0: a major update to the DrugBank database for 2018Nucleic Acids Res. 2017 Nov 846(D1):D1074-D1082
- DrugBank 4.02014Law V., Knox C., Djoumbou Y., et alDrugBank 4.0: shedding new light on drug metabolismNucleic Acids Res. 2014 Jan 142(1):D1091-7
- DrugBank 3.02011Knox C., Law V., Jewison T., et alDrugBank 3.0: a comprehensive resource for 'omics' research on drugsNucleic Acids Res. 2011 Jan39(Database issue):D1035-41
- DrugBank 2.02008Wishart D.S., Knox C., Guo A.C., et alDrugBank: a knowledgebase for drugs, drug actions and drug targets.Nucleic Acids Research2008 Jan36(Database issue):D901-6
- DrugBank 1.02006Wishart D.S., Knox C., Guo A.C., et alDrugBank: a comprehensive resource for in silico drug discovery and exploration.Nucleic Acids Research2006 Jan 134(Database issue):D668-72